re: Getting to I-10 E from Poydras, is it possible?

Yes you can. You have to take the road under the service roof and loop after Tulane. Or just take poydras to Roberts (side street by the supper dome). It Ts with Tulane and then you take a left and you are at the on ramp for 1-10 E. Or you can take the road under the interstate all the way to treme and there is another I-10E ramp. Hope that makes sense