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Lancet: Associations between body-mass index and COVID-19 severity in 6·9 million people
Posted on 4/30/21 at 1:17 pm
Posted on 4/30/21 at 1:17 pm
https://www.thelancet.com/journals/landia/article/PIIS2213-8587(21)00089-9/fulltext
TPA heuristic
If you cannot see your genitalia (truncal obesity) when standing, proceed with caution
If you are old and/or sickly, proceed with caution
If you are immunocompromised, proceed with caution
Everyone else is good
If you are scared, stay home (and stay off social media for fricks sake)...
quote:
Associations between body-mass index and COVID-19 severity in 6·9 million people in England: a prospective, community-based, cohort study
Min Gao, MSc *
Carmen Piernas, PhD *
Nerys M Astbury, PhD
Prof Julia Hippisley-Cox, FRCP
Prof Stephen O'Rahilly, FRS
Prof Paul Aveyard, FRCGP †
et al.
Show all authors
Show footnotes
Open Access
Published:April 28, 2021
quote:
Summary
Background
Obesity is a major risk factor for adverse outcomes after infection with SARS-CoV-2. We aimed to examine this association, including interactions with demographic and behavioural characteristics, type 2 diabetes, and other health conditions.
Methods
In this prospective, community-based, cohort study, we used de-identified patient-level data from the QResearch database of general practices in England, UK. We extracted data for patients aged 20 years and older who were registered at a practice eligible for inclusion in the QResearch database between Jan 24, 2020 (date of the first recorded infection in the UK) and April 30, 2020, and with available data on BMI. Data extracted included demographic, clinical, clinical values linked with Public Health England's database of positive SARS-CoV-2 test results, and death certificates from the Office of National Statistics. Outcomes, as a proxy measure of severe COVID-19, were admission to hospital, admission to an intensive care unit (ICU), and death due to COVID-19. We used Cox proportional hazard models to estimate the risk of severe COVID-19, sequentially adjusting for demographic characteristics, behavioural factors, and comorbidities.
Findings
Among 6?910?695 eligible individuals (mean BMI 26·78 kg/m2 [SD 5·59]), 13?503 (0·20%) were admitted to hospital, 1601 (0·02%) to an ICU, and 5479 (0·08%) died after a positive test for SARS-CoV-2. We found J-shaped associations between BMI and admission to hospital due to COVID-19 (adjusted hazard ratio [HR] per kg/m2 from the nadir at BMI of 23 kg/m2 of 1·05 [95% CI 1·05–1·05]) and death (1·04 [1·04–1·05]), and a linear association across the whole BMI range with ICU admission (1·10 [1·09–1·10]). We found a significant interaction between BMI and age and ethnicity, with higher HR per kg/m2 above BMI 23 kg/m2 for younger people (adjusted HR per kg/m2 above BMI 23 kg/m2 for hospital admission 1·09 [95% CI 1·08–1·10] in 20–39 years age group vs 80–100 years group 1·01 [1·00–1·02]) and Black people than White people (1·07 [1·06–1·08] vs 1·04 [1·04–1·05]). The risk of admission to hospital and ICU due to COVID-19 associated with unit increase in BMI was slightly lower in people with type 2 diabetes, hypertension, and cardiovascular disease than in those without these morbidities.
Interpretation
At a BMI of more than 23 kg/m2, we found a linear increase in risk of severe COVID-19 leading to admission to hospital and death, and a linear increase in admission to an ICU across the whole BMI range, which is not attributable to excess risks of related diseases. The relative risk due to increasing BMI is particularly notable people younger than 40 years and of Black ethnicity.
TPA heuristic
If you cannot see your genitalia (truncal obesity) when standing, proceed with caution
If you are old and/or sickly, proceed with caution
If you are immunocompromised, proceed with caution
Everyone else is good
If you are scared, stay home (and stay off social media for fricks sake)...
Posted on 4/30/21 at 1:22 pm to ThinePreparedAni
Yeah, I said back in April of 2020 that I wasn't worried about covid because I wasn't an obese mess of a human. If you're healthy, you have nothing to worry about
Posted on 4/30/21 at 1:25 pm to Pecker
quote:
If you're healthy, you have nothing to worry about
As a general rule I would be willing to accept the standard of "being able to see your dick" as the new criteria for social interactions
I kid...
quote:
Pecker
Posted on 4/30/21 at 1:25 pm to Pecker
those fat-shaming bastarfs!
This post was edited on 8/24/21 at 8:37 pm
Posted on 4/30/21 at 1:26 pm to ThinePreparedAni
Breaking news: Being fat increases your susceptibility to and makes it harder to fight illnesses.
Eating like shite and avoiding exercising has consequences
Eating like shite and avoiding exercising has consequences
Posted on 4/30/21 at 1:27 pm to ThinePreparedAni
quote:
If you cannot see your genitalia (truncal obesity) when standing, proceed with caution
This is what made me start losing weight a few years ago. Scared the shite out of me.
Posted on 4/30/21 at 1:27 pm to ThinePreparedAni
Wow, it took Lancet a year to find out what everybody else knew 12 months ago.
Posted on 4/30/21 at 1:28 pm to ThinePreparedAni
quote:
Black ethnicity
Of course the China Virus is racist against Black people!
Posted on 4/30/21 at 1:29 pm to ThinePreparedAni
So, let me get this straight...
Olds are high risk.
Fatties are high risk.
Dark skinned people (due to Vitamin D) are high risk.
So the Politard board has been right since day one. But we live in an alternate reality.
Olds are high risk.
Fatties are high risk.
Dark skinned people (due to Vitamin D) are high risk.
So the Politard board has been right since day one. But we live in an alternate reality.
Posted on 4/30/21 at 1:31 pm to ThinePreparedAni
Fat fricks are such a drain on society
Posted on 4/30/21 at 1:39 pm to ThinePreparedAni
Being fat drains vitamin D
Posted on 4/30/21 at 1:41 pm to Bestbank Tiger
quote:
So the Politard board has been right since day one. But we live in an alternate reality.
A low T alternate reality
TDS...
https://www.renalandurologynews.com/home/departments/mens-health-update/hypogonadism/testosterone-deficiency-low-t-risk-pro-inflammatory-foods/
quote:
April 29, 2021
Inflammatory Diet May Contribute to Testosterone Deficiency in Men
quote:
The mean total testosterone level was significantly lower in men with the most pro-inflammatory diet (highest tertile of DII) compared with men with the most anti-inflammatory diet (lowest tertile of DII): 410.42 vs 422.71 ng/dL, Shi Qiu, MD, and colleagues from West China Hospital, Sichuan University in China, reported in The Journal of Urology. The odds of testosterone deficiency increased 4.0% for every unit increase in DII. In a fully adjusted model, men in tertiles 2 and 3 had significant 19% and 30% increased odds of testosterone deficiency compared with men in tertile 1.
Obese men with more pro-inflammatory diets (tertiles 2 and 3) had 15.91 and 26.75 ng/mL lower total testosterone than men with an anti-inflammatory diet (tertile 1). Results showed that obese men in the higher DII tertiles had significant 31% and 59% increased odds of testosterone deficiency, respectively.
“Our results suggest men who eat a pro-inflammatory diet, particularly those who are obese, are more likely to have testosterone deficiency,” Dr Qiu stated in a press release from the journal’s publisher. “Since men with obesity likely already experience chronic inflammation, physicians should be aware of contributing factors, like diet, that could likely worsen this inflammation and contribute to the risk of other health conditions, such as diabetes and heart disease.”
An inflammatory diet is characterized by a higher content of refined carbohydrates, added sugars, saturated fat, and cholesterol, and a lower content of unsaturated fat, fiber, and polyphenols.
Problems in our country:
low T
no native balls
inappropriate allocation of "balls"
This post was edited on 4/30/21 at 1:54 pm
Posted on 4/30/21 at 1:49 pm to ThinePreparedAni
quote:
At a BMI of more than 23 kg/m2, we found a linear increase in risk of severe COVID-19 leading to admission to hospital and death
Wonder if findings like this may cause them to adjust the BMI scale to have 23 as the new border between healthy & overweight.
Can't wait for all the 6'2" posters to talk about how they're skeletons at 180 lbs
Posted on 4/30/21 at 1:57 pm to luvdoc
So there's a direct linear relationship between COVID illness severity, and fatness.
Just one more salient endorsement of a fibre-rich, low cholesterol, low trans fat vegan diet.
Just one more salient endorsement of a fibre-rich, low cholesterol, low trans fat vegan diet.
Posted on 4/30/21 at 2:06 pm to tarzana
quote:
Just one more salient endorsement of a fibre-rich, low cholesterol, low trans fat vegan diet.
These broad terms frustrate me
Minimize:
processed food (refined carbs)
sugar
factory farmed proteins (concentration camp protein)
My experience:
Vegans feel great for a while after getting rid of above (addition by subtraction). Later in time they return to feeling malaise / sickly/ weak due in large part to nutritional deficiencies from a restricted diet
There is room for:
well sourced meat - grass fed beef, wild seafood, organ meat
saturated fat/cholesterol - in small quantities from nutrient dense sources (meat and eggs)
More veggies and greens are a given.
Our evolved dentition is as such because we are ominvores (if you believe in science and shite...)
This post was edited on 4/30/21 at 2:10 pm
Posted on 4/30/21 at 2:26 pm to ThinePreparedAni
I have posted in other threads that a problem in Louisiana is people have come to accept obesity as normal since it is so common. Any mention of what the medical/ insurance community has promoted as a normal weigh range vs height usually provokes responses like “ if I weighed what the tables say for my height, I would look like a aids patient”! A recent thread about a 5’8” 260 lb dying from Covid19 had the comment that he was not severely overweight.
Posted on 4/30/21 at 2:28 pm to ThinePreparedAni
quote:Lancet admitted making up shite about HCQ last year. Why should I trust anything they print?
Lancet
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