re: New LDL cholesterol treatment

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A lot of people have this

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1:250 to be accurate. So this drug would only be for .3% of the population. Repatha does drop ldl into the teens, but investors were disappointed to learn that the reduction in mace was not linear, suggesting that under a certain point, there is no benefit and reducing LDL. Thomas Dayspring is the only person people need to listen to on cholesterol advice. Statin data can show a modest reduction in mace, but the idea is if you can do 10 of these things you can make a big difference in your health. It looks like the new weight loss drugs,GLP-1 are just as effective in reducing mace, and they’re finding benefit without weight loss, suggesting there is something intrinsically beneficial about the drug, and not just weight loss.

The benefit in a statin pales in comparison to the benefit of being less than 20% body, fat, walking 10,000 steps a day, zone 2 140 minutes a week, zone 4 10 minutes a week. In that order. After that you can worry about macros.

I have very high hdl, very low tri, and high ldl

Years ago I would be on a statin crushing my brain for no reason

My experience with HDL, LDL and Triglycerides also involve having a stent at 52. Mostly genetics but total cholesterol was normal; LDL (bad) was borderline high. HDL (good) was borderline low and Triglycerides were in the midrange. These are reported on a lipid profile and also calculated as cardiac ratio/index, a ratio between the three. This is the number we chose to focus on, mine was 5.2. Normal is about 5 to 3. Crestor 10mg to help lower LDL and get a bump up on the HDL. Exercising will also push HDL up. Zetia 10mg (works in the gut) to lower LDL. Changed my diet (less booze) to take Triglycerides down. I’m 66 now cardiac ratio stays around 2.5 and am very active. Lost my Dad and a brother in their early 50’s to heart attacks. Don’t smoke either. It can be done and there are different ways to it but it takes the commitment between you and your medical provider.

Agreed but weight lifting is more important than zone 2 and zone 4 on mace from what I have seen