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re: C-19 attacks Hemoglobin

Posted on 4/20/20 at 6:30 am to
Posted by MojoGuyPan
Intercession City, Florida
Member since Jun 2018
2797 posts
Posted on 4/20/20 at 6:30 am to
quote:

A Chinese study revealed some interesting facets about this bug.


You sure it wasn't a German study?
Posted by Strannix
C.S.A.
Member since Dec 2012
52944 posts
Posted on 4/20/20 at 6:41 am to
We knew this a month ago
Posted by Volvagia
Fort Worth
Member since Mar 2006
52917 posts
Posted on 4/20/20 at 6:57 am to
Thank you.

It’s amazing to me how often these people who aren’t scientifically literate are latching on these pre prints as evidence.

The paper even says they need external confirmation in the quoted text.


Posted by Volvagia
Fort Worth
Member since Mar 2006
52917 posts
Posted on 4/20/20 at 7:04 am to
quote:

The easiest way to think of it might be this: covid shouldn’t be thought of as a respiratory disease, but a disease of the blood (hematologic). The virus prevents your red blood cells from carrying oxygen throughout the body and exchanging carbon dioxide and oxygen in the lungs. So the virus’s attack on red blood cells is what is causing the lung disease you’re hearing about.



No no NO

This paper doesn’t claim ANY of that.

There is no expected mechanism of this virus infecting red blood cells.

Also, mature human red blood cells can’t support viral replication anyway so it’s a dead end for them.

All they did was notice some proteins have similarity to other known proteins that have been mathematically characterized, and in a computer model it could chemically act in the manner they describe which could possibly translate to the clinical reaction.

They are basing this all by making assumptions based on the genetic sequence because they haven’t solved the 3 dimensional structure of the nCoV proteins yet

There is ZERO experimental data provided here that it actually works that way. Which is why they requested in the abstract for other labs to follow through their “nifty idea.”

If COVID-19 was so heavily blood based, we would see more systemic symptoms like we did with SARS.
This post was edited on 4/20/20 at 7:09 am
Posted by mdomingue
Lafayette, LA
Member since Nov 2010
42930 posts
Posted on 4/20/20 at 7:08 am to
quote:

Because it's a chinese study?

Well, my little klukker, it was Chinese doctors who sounded the alarm and were thrown in jail by the commies. It was Chinese doctors who were on the front lines and died fighting the virus.






So we should believe the doctors who haven't been and don't want to be thrown in jail and tortured to be telling us the truth?

Or should we be a little skeptical until other independent studies also corroborate this? Although this does make sense given what we do know, right now a Chinese study seems like it's just a step above anecdotal.
Posted by PrimeTime Money
Houston, Texas, USA
Member since Nov 2012
27873 posts
Posted on 4/20/20 at 8:43 am to
Posted by Yewkindewit
Near Birmingham, Alabama
Member since Apr 2012
21626 posts
Posted on 4/20/20 at 8:54 am to
Should spell it “ahs-horr”.
Posted by real turf fan
East Tennessee
Member since Dec 2016
11294 posts
Posted on 4/20/20 at 10:34 am to
Is there something about Subsaharan blood that is tied to this? The much higher mortality rates among some ethnic groups that might be carriers of unexpressed sickle cell traits might be worth looking at.
Has anyone with Sickle Cell showed expressed serious symptoms of Co19?
Posted by dbeck
Member since Nov 2014
29454 posts
Posted on 4/20/20 at 10:40 am to
quote:

molecular docking

Posted by TheCaterpillar
Member since Jan 2004
76774 posts
Posted on 4/20/20 at 10:49 am to
The real question is what essential oils can fight this
Posted by YipSkiddlyDooo
Member since Apr 2013
3786 posts
Posted on 4/21/20 at 12:48 am to
quote:


No no NO


The person I was responding to was asking for a layman’s way to understand the Chinese paper.

quote:

This paper doesn’t claim ANY of that.

There is no expected mechanism of this virus infecting red blood cells.

Also, mature human red blood cells can’t support viral replication anyway so it’s a dead end for them.


I never said that the virus infected red blood cells. Neither does the paper. The virus lives and replicates in surrounding cells, then “attacks” and binds the passing porphyrin.

quote:

There is ZERO experimental data provided here that it actually works that way. Which is why they requested in the abstract for other labs to follow through their “nifty idea.”


What does this have to do with trying to help someone understand the paper? Did I make the claim that the mechanism proposed in the paper was correct?

quote:

If COVID-19 was so heavily blood based, we would see more systemic symptoms like we did with SARS.


Da fuq? We have seen cardiac pathology due to the virus. Renal failure. Emboli in the extremities. Cutaneous manifestations in the feet. Neurologic disease...
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