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re: SSRI/SNRI med question?

Posted on 12/15/16 at 9:39 pm to
Posted by martiallaw
Louisiana
Member since Jan 2008
1458 posts
Posted on 12/15/16 at 9:39 pm to
Have you done any genetic testing? You are probably a CYP2C19 poor metabolizer and/or a SLC6A4 Short/Short or Long/Short if you went from a SSRI to a SNRI and had better results.
Posted by WarmBubble
Member since May 2007
1891 posts
Posted on 12/15/16 at 10:11 pm to
quote:

Have you done any genetic testing? You are probably a CYP2C19 poor metabolizer and/or a SLC6A4 Short/Short or Long/Short if you went from a SSRI to a SNRI and had better results.


This.

Don't let anyone tell you to get off a drug because "someone I know" had a bad experience with the drug.

I know several people who have responded well to 1-2 SSRI's, but not other SSRI's. Some responded well to all the SNRI's but no SSRI's.

Don't let anyone tell your Cymbalta or Effexor is better than the other. Both are in the same class, but response, SE profile, and discontinuation syndrome all different for each person.

Listen to your doctor.

You may need an increased dose. But don't do this own your own. It is also common for some meds to stop working as well as they did several months ago. Just be patient. If you can afford generic testing, go for it.



Posted by RandySavage
Member since May 2012
30971 posts
Posted on 12/16/16 at 10:35 am to
quote:

Have you done any genetic testing? You are probably a CYP2C19 poor metabolizer and/or a SLC6A4 Short/Short or Long/Short if you went from a SSRI to a SNRI and had better results.


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