quote:
They just had a big study released on a new drug that increases your HDL 30% and decreases your LDL by 130%. The study was supposed to revolutionize heart disease. But what they found out was shocking. There was no decrease mortality, and heart attack. So what the study concluded is that it's not about the numbers, it may be about how cholesterol is made and processed. When I conclude is that they don't know shite.

Cholesterol is a lipid protein meaning it contains fat and protein. Ingested cholesterol would not be immediately shot into your blood stream because it is an animal/plant product, i.e. foreign antigen, which would trigger an immune response.

Cholesterol in the blood stream is produced by your body to protect damaged or inflamed areas. So, your cholesterol level is more of a indication of general inflammation. This general inflammation could have many sources, one of which is a shitty diet. Another cause which has been hypothesized is excessive cardiovascular exercise (hardcore distance runners and cyclists, not your run 10 miles a week, 5k warrior).

In other words, high-cholesterol foods are fine to eat, but like anything, excess will frick you up.

This post was edited on 4/27/16 at 8:18 am

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Posted by Rust Cohle

Baton rouge

Member since Mar 2014

1977 posts

Posted on 4/27/16 at 8:30 am to guedeaux

The drug is Evacetrapib. LINK

I asked the cardiologist I work with what they thought about it, Most said oh yeah I think I read that. I told one that I feel that we really don't have a great understanding on how cholesterol works, he said yes, we are just really treating numbers.

I told him about how I thought statins don't really reduce mortality and how I remember seeing on the commercials it even said so, (you know when the guy was walking along the beach.)

He reassured me I was mistaken, and that statins have an extra inflammatory property.

From the few studies I have recently looked at the best reduction in heart attack and cardiovascular disease is 25%, which is nothing to Scoff at. But here's the kicker if you don't have heart disease, it only decreases your chances of a heart attack or related event by 1%, and increases your chance of diabetes,dementia, and cataracts and I imagine joint pain where cholesterol is very needed.

This post was edited on 4/27/16 at 8:36 am

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Posted by tiger91

In my own little world

Member since Nov 2005

36817 posts

Posted on 4/27/16 at 10:13 am to guedeaux

quote:
Another cause which has been hypothesized is excessive cardiovascular exercise (hardcore distance runners and cyclists, not your run 10 miles a week, 5k warrior).

I had run a half marathon 3-4 days prior to the bloodwork .. I'm wondering if/how this affected the hsCRP.

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Posted by Upperaltiger06