re: how would you re-align mlb divisions?

If you want to change baseball's divisions in a rational way you probably have to increase the total number of teams by two to get to 32 total. Then you have the potential for four divisions in both leagues.

Let's arbitrarily make the case that Sacramento and Austin are your expansion sites (large states with well supported baseball attendance, affluence, etc) because San Jose is SF territory, Las Vegas brings gambling and the other probable sites like Montreal, Providence, Charlotte, and Memphis don't look like they would have the combination of affluence and population to support a 162 game season.

Then you could talk about moving around a few teams while keeping intact a few blocks like:

yankees, red sox, orioles
cardinals, cubs, reds +/- pirates
phillies, mets
dodgers, giants, padres
tigers, twins, white sox, indians
A's, mariners