re: Animal protein and endothelial damage

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but to each their own but tell her to look into studies on pomegranate juice

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I did tell her and also suggested Nattokinase. It’s frustrating to see them
abandoning meat while they simultaneously lose muscle mass. They’ll abandon their diet of 70 years for peas and lentils but won’t lift a weight heavier than the remote.

The abstract on that paper has a lot of “may do” this or that. Also, what seems to me to be prevalent in the mainstream narrative on this stuff is a lot of correlation equals causation which is passed off as proof.

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Atherosclerosis associated with high dietary intake of meat, fat, and carbohydrates remains the leading cause of mortality in the US. This condition results from progressive damage to the endothelial cells lining the vascular system, including the heart, leading to endothelial dysfunction. In addition to genetic factors associated with endothelial dysfunction, many dietary and other lifestyle factors, such as tobacco use, high meat and fat intake, and oxidative stress, are implicated in atherogenesis. Polyphenols derived from dietary plant intake have protective effects on vascular endothelial cells, possibly as antioxidants that prevent the oxidation of low-density lipoprotein. Recently, metabolites of L-carnitine, such as trimethylamine-N-oxide, that result from ingestion of red meat have been identified as a potential predictive marker of coronary artery disease (CAD). Metabolism of L-carnitine by the intestinal microbiome is associated with atherosclerosis in omnivores but not in vegetarians, supporting CAD benefits of a plant-based diet. Trimethylamine-N-oxide may cause atherosclerosis via macrophage activation. We suggest that a shift toward a plant-based diet may confer protective effects against atherosclerotic CAD by increasing endothelial protective factors in the circulation while reducing factors that are injurious to endothelial cells.

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