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The 2-repeat Allele of the MAOA Gene Confers an Increased Risk

Posted on 2/26/22 at 10:11 am
Posted by Upshift Downshift
Red Stick
Member since Feb 2022
381 posts
Posted on 2/26/22 at 10:11 am
for shooting and stabbing behaviors.


Abstract

There has been a great deal of research examining the link between a polymorphism in the promoter region of the MAOA gene and antisocial phenotypes. The results of these studies have consistently revealed that low activity MAOA alleles are related to antisocial behaviors for males who were maltreated as children.

Recently, though, some evidence has emerged indicating that a rare allele of the MAOA gene-that is, the 2-repeat allele-may have effects on violence that are independent of the environment. The current study builds on this research and examines the association between the 2-repeat allele and shooting and stabbing behaviors in a sample of males drawn from the National Longitudinal Study of Adolescent Health.

Analyses revealed that African-American males who carry the 2-repeat allele are significantly more likely than all other genotypes to engage in shooting and stabbing behaviors and to report having multiple shooting and stabbing victims. The limitations of the study are discussed and suggestions for future research are offered.

PubMed Link


Posted by Lima Whiskey
Member since Apr 2013
22594 posts
Posted on 2/26/22 at 10:14 am to
Yup.
Posted by El Segundo Guy
SE OK
Member since Aug 2014
10960 posts
Posted on 2/26/22 at 10:16 am to
This is why we need more programs.
Posted by Jimbeaux
Member since Sep 2003
20940 posts
Posted on 2/26/22 at 10:18 am to
quote:

Analyses revealed that African-American males who carry the 2-repeat allele are significantly more likely than all other genotypes to engage in shooting and stabbing behaviors and to report having multiple shooting and stabbing victims.


Regarding this 2-repeat allele, is it only found in African males, or more prevalently found in them? Is that what the article is saying?
Posted by 3lsu3
Member since Sep 2004
4691 posts
Posted on 2/26/22 at 10:22 am to
Is this furthering the warrior gene concept? I haven’t started digging in. If so, it runs through many Mediterranean “white” bloodlines as well.

ETA: it is, just looked it up. Some theories out there it was spread into other populations during Roman times of conquest.
This post was edited on 2/26/22 at 10:26 am
Posted by Penrod
Member since Jan 2011
47679 posts
Posted on 2/26/22 at 10:23 am to
quote:

African-American males who carry the 2-repeat allele are significantly more likely than all other genotypes to engage in shooting and stabbing behaviors and to report having multiple shooting and stabbing victims.

African-American males who carry shortness genes are significantly more likely than all other genotypes to engage in shooting and stabbing behaviors and to report having multiple shooting and stabbing victims.

African-American males who carry tallness genes are significantly more likely than all other genotypes to engage in shooting and stabbing behaviors and to report having multiple shooting and stabbing victims.

African-American males who carry [FILL IN GENE HERE] are significantly more likely than all other genotypes to engage in shooting and stabbing behaviors and to report having multiple shooting and stabbing victims.
Posted by Lima Whiskey
Member since Apr 2013
22594 posts
Posted on 2/26/22 at 10:42 am to
I think it’s old research. The people who called it the warrior gene got into political trouble because of it.

It was an unthinkable idea.
Posted by 3lsu3
Member since Sep 2004
4691 posts
Posted on 2/26/22 at 10:44 am to
If you google the terms together, seems like many are still calling it that. And lol, to the last bit.

I’ll try to dig up something I watched by an American psych with Italian bloodlines who carries it himself.
This post was edited on 2/26/22 at 10:47 am
Posted by fr33manator
Baton Rouge
Member since Oct 2010
130802 posts
Posted on 2/26/22 at 10:46 am to
quote:

The people who called it the warrior gene got into political trouble because of it. It was an unthinkable idea.


Perhaps the “Shooty-Looty” gene is a better moniker.
Posted by joshnorris14
Florida
Member since Jan 2009
45967 posts
Posted on 2/26/22 at 12:12 pm to
quote:

Regarding this 2-repeat allele, is it only found in African males, or more prevalently found in them? Is that what the article is saying?


It's significantly more prevalent in blacks than other races. I believe white's are 20% as likely to have it, Asians are less than 1% as likely to have it
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