I only make one bracket - downvote away (winners in ALL CAPS)

SOUTH:

(1) AUBURN vs (16) Alabama State
(8) LOUISVILLE vs (9) Creighton
(5) Michigan vs (12) UC SAN DIEGO
(4) TEXAS A&M vs (13) Yale
(6) Ole Misss vs (11) NORTH CAROLINA
(3) IOWA STATE vs (14) Lipscomb
(7) MARQUETTE vs (10) New Mexico
(2) MICHIGAN ST vs (15) Bryant

(1) Auburn vs (8) LOUISVILLE
(4) TEXAS A&M vs (12) UC San Diego
(3) Iowa State vs (11) NORTH CAROLINA
(2) MICHIGAN ST vs (7) Marquette

(4) Texas A&M vs (8) LOUISVILLE
(2) MICHIGAN ST vs (11) North Carolina

(2) MICHIGAN ST vs (8) Louisville - MICHIGAN ST to FINAL FOUR

WEST:

(1) FLORIDA vs (16) Norfolk State
(8) UCONN vs (9) Oklahoma
(5) Memphis vs (12) COLORADO STATE
(4) MARYLAND vs (13) Grand Canyon
(6) Missouri vs (11) DRAKE
(3) TEXAS TECH vs (14) UNC-Wilmington
(7) KANSAS vs (10) Arkansas
(2) ST JOHN'S vs (15) Omaha

(1) FLORIDA vs (8) Uconn
(4) MARYLAND vs (12) Colorado State
(3) TEXAS TECH vs (11) Drake
(2) ST JOHN'S vs (7) Kansas

(1) FLORIDA vs (4) Maryland
(2) St John's vs (3) TEXAS TECH

(1) FLORIDA vs (3) Texas Tech - FLORIDA TO THE FINAL FOUR

EAST:

(1) DUKE vs (16) Mt St Mary's
(8) Mississippi State vs (9) BAYLOR
(5) OREGON vs (12) Liberty
(4) Arizona vs (13) AKRON
(6) BYU vs (11) Virginia Commonwealth
(3) WISCONSIN vs (14) Montana
(7) St. Mary's vs (10) VANDY
(2) ALABAMA vs (15) Robert Morris

(1) DUKE vs (9) Baylor
(5) OREGON vs (13) Akron
(3) WISONSIN vs (6) Byu
(2) ALABAMA vs (10) Vandy

(1) DUKE vs (5) Oregon
(2) ALABAMA vs (3) Wisconsin

(1) DUKE vs (2) Alabama - DUKE to FINAL FOUR

MIDWEST:

(1) HOUSTON vs (16) SIU-Edwardsville
(8) GONZAGA vs (9) Georgia
(5) CLEMSON vs (12) McNeese St
(4) PURDUE vs (13) High Point
(6) ILLINOIS vs (11) Xavier
(3) KENTUCKY vs (14) Troy
(7) Ucla vs (10) UTAH STATE
(2) TENNESSEE vs (15) Wofford

(1) HOUSTON vs (8) Gonzaga
(4) Purdue vs (5) CLEMSON
(3) Kentucky vs (6) ILLINOIS
(2) TENNESSEE vs (10) Utah State

(1) HOUSTON vs (5) Clemson
(2) TENNESSEE vs (6) Illinois

(1) HOUSTON vs (2) Tennessee - HOUSTON to FINAL FOUR

FINAL FOUR:

(W) FLORIDA vs (S) Michigan State
(E) DUKE vs (MW) Houston

FLORIDA over Duke

FLORIDA WINS THE NATIONAL CHOMPionship