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re: Best diet plan to lower cholesterol//LDL/Triglicerides

Posted on 11/27/24 at 7:51 pm to
Posted by Shepherd88
Member since Dec 2013
4881 posts
Posted on 11/27/24 at 7:51 pm to
[
quote:

For example, saturated fat appears to decrease small-dense LDL (sdLDL) and increase large buoyant LDL.3 As a high concentration of sdLDL and a low concentration of large buoyant LDL is associated with an increased risk of coronary heart disease (CHD),4 saturated fat may not necessarily increase the risk of CHD. Furthermore, compared with LDL-C, sdLDL (and oxidised LDL) seem to have a greater impact on atherosclerosis and cardiovascular disease.5


This section is contradicting itself. It’s saying saturated fat (omega 3) raise large buoyant sub particles which is correct. However sLDL is the one that causes plaque build up. It goes on after that sentence to clarify and state correctly that oxdidation of sLDL does have a correlated effect to CHD.


You can also read a lot more about this in “The Big Fat Surprise” by Nina Teicholz who will likely be in charge of the new Dietary Guidelines under RFK.
This post was edited on 11/27/24 at 8:04 pm
Posted by NewOrleansBlend
Member since Mar 2008
1179 posts
Posted on 11/27/24 at 8:10 pm to
I think the first sentence of that excerpt is mistyped or erroneous as it doesn’t fit with the studies cited in the review.
Posted by Shepherd88
Member since Dec 2013
4881 posts
Posted on 11/27/24 at 8:13 pm to
All you gotta do is google this baw to realize what you’re saying is incorrect
Posted by NewOrleansBlend
Member since Mar 2008
1179 posts
Posted on 11/27/24 at 8:29 pm to
Show me a controlled study or studies that show this. I have searched for it and can’t find it. All I see is a lot of people parroting that statement but no data.

Data for small LDL being associated with insulin resistance and carb intake is easily found.
This post was edited on 11/27/24 at 8:33 pm
Posted by Shepherd88
Member since Dec 2013
4881 posts
Posted on 11/27/24 at 8:35 pm to
There’s no such thing as a “controlled” study in human beings. It’s not possible. And that’s the point against science.

My point is what you just said though, carb intake and sugar increase small particle ldl which is associated with chd. Saturated fat increase large particle ldl and is not associated with chd.
Posted by NewOrleansBlend
Member since Mar 2008
1179 posts
Posted on 11/27/24 at 9:16 pm to
Studies absolutely can be controlled. Maybe not perfectly controlled, but a good study removes as many variables as possible. Nutrition studies are generally terrible quality and often involve food questionnaires which are completely worthless. However there are good nutrition studies that are done on a metabolic ward with every calorie and nutrient controlled. Pennington does these.

Speaking of, here is a study done in a metabolic ward that showed that increasing saturated fat increased LDL particle size. It was in people with metabolic syndrome which is a weakness.
LINK

I found a study that purports to show increased saturated fat intake was associated with larger ldl particles. However it’s a poorly designed study. It appears to be a subsequent analysis of a study comparing a high fat diet, which included all types of fats, and a low fat diet. It seems they used a food log to determine who consumed more SFAs than others. The fact that it’s a subsequent analysis (which often in research means the scientific method was done in reverse: a statistically significant difference was found then the hypothesis was asked) and relies on food logs makes the conclusion dubious.
LINK

ETA: Here’s a better designed study from the same senior author as the questionable study above which comes to the opposite conclusion: increased small and medium LDL’s with increased saturated fat intake. Quality is in between the two stories above, not in a metabolic ward, but the study was prospective, patients were randomized, they were healthy (not insulin resistant, normal triglycerides), researchers doing the lipid and data analysis were blinded to patient group, patients were provided food, etc.
LINK

This post was edited on 11/28/24 at 9:30 am
Posted by WAR TIGER
Death Valley
Member since Oct 2005
4269 posts
Posted on 11/28/24 at 12:50 am to
Crestor 10 mg. And keep rolling
This post was edited on 11/28/24 at 4:31 pm
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