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re: Why are people so fat now compared to just 30 years ago?
Posted on 9/1/21 at 8:01 pm to Unobtanium
Posted on 9/1/21 at 8:01 pm to Unobtanium
quote:
Simple answer - HFCS
Complex answer - HFCS and other highly processed foods and lack of exercise.
Yes.
90% of fructose gets converted to fat whereas only 10% of glucose (aka, dextrose) gets converted to fat (in the liver). Fructose is in everything. It is also a leptin blocker. Leptin is a hormone that makes you feel full.
FWIW, ethanol and fructose are processed the same in the liver. 90% converted to fat. However the difference between ethanol and fructose is, ethanol you get feedback. You get too drunk and stop drinking (most of us anyway). With fructose you just move on to the next sweet thing. Kids probably eat enough fructose in one day that is equivalent to drinking a six pack of beer.
This post was edited on 9/1/21 at 8:03 pm
Posted on 9/1/21 at 8:29 pm to GumboPot
quote:
FWIW, ethanol and fructose are processed the same in the liver
What do you mean processed the same? Fructose is made into F1P by fructokinase, and then is made into 2 molecules of glyceraldehyde-3-P, which can enter glycolysis. Because there is no rate-limiting step, there is an excess of triose metabolites, and fructose potentiates pyruvate kinase, leading to G3P also being being metabolized into pyruvate directly, which can go into multiple pathways. Ethanol is oxidized to acetaldehyde by alcohol dehydrogenase and then that is made into acetate by acetaldehyde dehydrogenase.
Pyruvate can become acetyl-CoA, which can lead to FA synthesis.
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