re: Is this the year a #16 seed upsets a #1 seed?

No.

But... FGCU at least has a puncher's chance of pulling the upset over UNC. They won't, mind you, but they are one of the best 16 seeds in memory and I do have faith in Roy Williams' ability to pull a fantastic choke job. i wouldn't predict it or anything, or even say it's likely, but I can at least envision FGCU pulling an upset if everything breaks right.

Also, UVA plays at such a slow pace, they may not put away Hampton. Again, really unlikely, but within the realm of possibility. Don't put any money on it.