Driving with the Family to California, which route and other suggestions?

We're going to drive from South Louisiana to Los Angeles over Easter to see family. We're also going to drive up the PCH and spend a few nights in Big Sur.

We've already got our trip in CA planned out, but wondering if there are suggestions as far as which route to take (i-10/1-20/i-40 are all about 26 hours each) and cool stops and must-sees on the way.

Thanks in advance.