re: Patients taking Eli Lilly's retatrutide lost 58 pounds, on average, in a phase 2 clinical

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I agree with you in principle, but, at the same time, Americans are fat as frick. And I have little hope that greater than 5% of Americans are going to do anything to improve their diets. Maybe you are anticipating a wave of healthy eating and personal accountability but I am not so optimistic.

As cold as it may sound, IMO, all these new weight loss drugs are dependent on cost/benefit. Do the potential benefits of these drugs in regards to money saved on treating chronic diseases caused by obesity outweigh the side-effects?

Americans aren't going to change their lifestyles. That's on them. Will these drugs help curb the ridiculous amounts of money spent on healthcare for fat people? I don't know, but if so they should put it in the tap water.

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Perpetual reliance on the drug isn't the answer. Since they do not change their lifestyle, they will have to stay on the drug 24/7 or just become a huge fat-arse again.