re: Buying window and aisle seats on a 3 seat setup

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There’s definitely undersold flights during off peak times

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There are only so many flights per day on INTL routes from USA hub cities like DTW, MSP, IAD, IAH, etc. There are often restrictions on how early the flights can land based upon the destination. Just picking a random flight based on another thread, Houston to Rome in August, there is NOTHING in the first 25 ITA Matrix results that lands after 0800. Yes, you can find ways to extend layovers at AMS, LHR, etc, to land later, but then you're wasting time.

But the point is, the flight time from EWR to FCO, for instance, will NOT change. What you choose to do to get to EWR, or what you choose as your connection to FCO, or what you choose to do after you leave FCO, is a preference issue.