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re: One Simple Question Regarding Mandatory Vaxes...
Posted on 10/15/21 at 5:52 pm to Tomatocantender
Posted on 10/15/21 at 5:52 pm to Tomatocantender
There is one, Novavax, that is delayed to manufacturing problems. May get EUA end of year or early next year.
Nebraska Medicine link
The Novavax COVID-19 vaccine contains a protein (made using moth cells) plus an adjuvant (made from tree bark). An adjuvant is an ingredient added to boost a person's immune response, creating higher levels of antibodies.
The Novavax vaccine uses a telltale piece of the coronavirus: the notorious spike protein. All alone, the spike protein is harmless and can't cause COVID-19. When your immune system encounters the lonely spike protein, it produces antibodies against it. This gives you protection against future COVID-19 infection.
"Unlike mRNA vaccines, the spike protein is already premade in the Novavax vaccine. It's a shortcut," explains Dr. Florescu. "All the synthesis happens outside the body and we just give the end product: the spike protein."
Yale medicine
How it works: Unlike the mRNA and vector vaccines, this is a protein adjuvant (an adjuvant is an ingredient used to strengthen the immune response). While other vaccines trick the body’s cells into creating parts of the virus that can trigger the immune system, the Novavax vaccine takes a different approach. It contains the spike protein of the coronavirus itself, but formulated as a nanoparticle, which cannot cause disease. When the vaccine is injected, this stimulates the immune system to produce antibodies and T-cell immune responses.
Nebraska Medicine link
The Novavax COVID-19 vaccine contains a protein (made using moth cells) plus an adjuvant (made from tree bark). An adjuvant is an ingredient added to boost a person's immune response, creating higher levels of antibodies.
The Novavax vaccine uses a telltale piece of the coronavirus: the notorious spike protein. All alone, the spike protein is harmless and can't cause COVID-19. When your immune system encounters the lonely spike protein, it produces antibodies against it. This gives you protection against future COVID-19 infection.
"Unlike mRNA vaccines, the spike protein is already premade in the Novavax vaccine. It's a shortcut," explains Dr. Florescu. "All the synthesis happens outside the body and we just give the end product: the spike protein."
Yale medicine
How it works: Unlike the mRNA and vector vaccines, this is a protein adjuvant (an adjuvant is an ingredient used to strengthen the immune response). While other vaccines trick the body’s cells into creating parts of the virus that can trigger the immune system, the Novavax vaccine takes a different approach. It contains the spike protein of the coronavirus itself, but formulated as a nanoparticle, which cannot cause disease. When the vaccine is injected, this stimulates the immune system to produce antibodies and T-cell immune responses.
Posted on 10/15/21 at 7:01 pm to MandevilleMike
quote:
It contains the spike protein of the coronavirus itself, but formulated as a nanoparticle
Can anyone explain "formulated as a nanoparticle" to me?
So the Novavax also just uses the spike? Wouldn't that make it ineffective against variants with a mutated spike, like the current vacs are against Delta and other variants with mutated spikes?
When all of this BS started I saw a clip of an old dude talking about why there had never been a successful vaccine for any coronavirus.. something to do with binding vs non binding particles.
I don't know what that means, but every time I hear about vax and the spike it makes me wonder... Is that why all the vaccines only use the spike?
Posted on 10/15/21 at 7:16 pm to MandevilleMike
quote:
There is one, Novavax, that is delayed to manufacturing problems.
Correct and I've been following its roller coaster stock price since the summer. I have no faith that it ever gets brought to market, at least not in time for the mandate and a choice to lose your job or not. Another one I follow is ticker DYAI and their partner Sorrento.
This post was edited on 10/15/21 at 7:17 pm
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