re: What if there is never a vaccine?

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The vaccine, if we develop one will likely be no more effective than a conventional flu vaccine......

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We guess as to the next season's flu strain in order to lead with a vaccine. If we guess wrong or more than one strain circulates, the flu shot is ineffective. Flu also is quite mutable, adding to the challenge.

In the case of a CV19 vaccine, we're not guessing as to the virus. CV19 is less prone to mutation. Finally, if Jenner Institute findings hold, an HCoV vaccine targeting spike proteins might not even need to be specific for CV19, which is very encouraging.

Finally, even if the thing was only 60% effective, widespread application would generate de facto herd immunity.