quote:
I’ve had a very strong suspicion for awhile now that anemic patients do very poorly with this. I thought it was primarily due to the severe pneumonia impairing oxygen delivery but this makes sense

I know you are a pharmacist, so I have a question that wasn't answered when we did pharm. We learned about the retinal toxicity associated with chloroquine. The risk factors for that, such as advanced age and and obesity, coincide with the risk factors for Covid-19. Do you think there is some hesitance on using hydroxychloroquine based on how the risk factors for retinopathy are the same risk factors for this disease? I apologize if this is a really elementary question. Our pharm course was super quick and did surface level discussions of when to use the drugs.

This post was edited on 4/7/20 at 8:37 am

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Posted by Tiguar

Montana

Member since Mar 2012

33131 posts

Posted on 4/7/20 at 8:41 am to crazy4lsu

I don’t think that’s the reason, no. The retinopathy is usually seen after longer courses with accumulation of drug. The risk of retinopathy with a 5 day course is very low.

And don’t feel bad, I feel like we got very little pharm too

Probably 90% of what I know I learned in 4th year and residency

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Posted by CrimsonTideMD

Member since Dec 2010

6925 posts

Posted on 4/7/20 at 10:48 am to crazy4lsu

quote:
We learned about the retinal toxicity associated with chloroquine. The risk factors for that, such as advanced age and and obesity, coincide with the risk factors for Covid-19. Do you think there is some hesitance on using hydroxychloroquine based on how the risk factors for retinopathy are the same risk factors for this disease?

Others please correct me if I'm wrong, but IIRC there's a significant difference in the side effect/risk profile between hydroxychloroquine and chloroquine, the latter being more serious/dangerous.

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