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re: Biology, Chemist and Biochemist OTers: Help me understand weight loss.

Posted on 4/3/17 at 8:28 am to
Posted by Junky
Louisiana
Member since Oct 2005
8415 posts
Posted on 4/3/17 at 8:28 am to
quote:

My understanding isn't necessarily that you will burn glucose first. It is just an "easier" source of fuel. It can be broken down into energy more quickly. Therefore, at higher rates of physical exertion, you will burn glucose energy stores. When you run low, you get that bonked/drained feeling and you have no more fuel in the tank (fat can't break down fast enough to supply the energy). At lower rates of energy exertion, your body can run on fat energy stores. It's all about your heart rate and metabolic zone.

This is where people see that "fat burning zone" on the treadmill and think they need to work out in that zone to burn their fat. That's not necessarily a truthful idea. You don't lose weight 'better' just because you burned fat in that zone. You are just utilizing that as a source of energy at that level of physical exertion. In the end, you burned X amount of calories. If you burned X amount of calories in the "glucose burning zone" you'd have done the same amount of good in terms of weight loss. The source of energy just becomes more important in endurance sports like running a marathon or something.

I don't claim to be an expert. My input is about as good as any other bro-science out there. Just from a different perspective when researching running/triathlon nutrition.


Pretty much this. Ketosis isn't going to help you lose weight faster, it is a state of fuel burning for the body. Most people burn glucose because we constantly dump excess sugar/complex carbs into our system and we do not give our bodies a chance to rid ourselves of it.

Think of it as stages of fuel - The body prefers burning fat but must rid itself of other, maybe harmful, fuels first. The body burns ethanol off first and foremost as it can be poisonous. Then switches to glucose until it is in safe levels in the bloodstream. Once glucose levels are safe, it will switch and run off fat.

We carry fat around on our bodies as a storage tank for fuel in case of emergencies. It is much easier and efficient to carry around that much energy in fat than any other substance. Protein is extremely taxing on the body to break down. Gluconeogenesis is a demand driven pathway that wont start unless it absolutely needs to - it is not supply driven. Hormones are very important to have corrected because they will determine fat storage. Basically, if your body doesn't recognize the fat on you, it wants to store more.
Posted by zatetic
Member since Nov 2015
5677 posts
Posted on 4/3/17 at 9:09 am to
Ketosis (which is a high fat diet) uses fat as energy. All the other diets uses glucose as energy.

So if you are on a diet to lose weight ketosis is best. It keeps your hormones in great shape, because hormones are from fat and you won't lose muscle because muscle cannot break down into ketones but it can break down into glucose. Fatty food is hard to break down and burns quite a bit of energy trying to process it. It is why if you eat a fatty food you will feel warmer because your expending energy trying to digest it. Les Stroud even pointed out eating straight fat right before sleeping is great help to keep warm when he was survivormanning it up in some cold area. Ketosis gives the benefits of fasting while still eating. It theoretically may be impossible to get cancer while in ketosis since you will have no glucose for the cancer to use (this is a big leap of faith but it is known to help treat cancer). What I've read says no one can get approval to do an actual study with human subjects on whether a ketosis diet can treat cancer.

In all the other diets fat is typically the last thing to lose because it is the hardest thing to breakdown into glucose. Sugar is inflammatory for your whole body. Cancer runs on glucose. Literally almost everything bad healthwise comes from sugar and grains. If you aren't using the energy immediately it turns into fat because it takes no energy to breakdown sugar and grains.
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