re: If they do this to our food, and they do this to our water

Below is part of my response to similar question in a different thread:

If I were trying to design a society (or a market for pharmaceuticals...) that was:

Obese
Apathetic
Testosterone deficient
Cognitively impaired

I would have them eating and drinking the crap our society does....


Undervalued response (primary prevention through practical lifestyle recommendations and PROPER dietary recommendations for the masses...):

Below addresses food quality and exposures....

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9 Steps To Perfect Health

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non-pdf version

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Despite these considerable advances, we’re sicker and fatter than ever before. Consider the following:
• Excess weight now accounts for one in three deaths among middle aged people in the US each year.
• A billion people around the world suffer from diabetes and obesity.
• 600 thousand people die of heart attacks in the US each year.
• One-third of Americans suffer from high blood pressure, which contributes to almost 800 thousand strokes every year.
• 50 million people in the US—one in six Americans—suffer from autoimmune diseases like Hashimoto’s, rheumatoid arthritis, multiple sclerosis, and Crohn’s disease.
• Depression is now the leading cause of disability, affecting more than 120 million people worldwide.
Unfortunately, there’s every indication that things are going to get worse before they get better. This is the first generation of American children that are expected to live shorter lifespans than their parents. If current trends continue, 95 percent of Americans are expected to be overweight or obese within two decades, and one in three will suffer from diabetes.

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See link below with mTOR (IGF-1 pathway)

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Finding a Balance Between Building and Repair: Part 1

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LINK

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Finding a Balance Between Building and Repair: Part 2 Intermittent Fasting

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LINK





Ever wonder why obese people look older than their stated age...

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Building (growth) is an anabolic process that happens when mTOR is turned on. Stimuli such as resistance training and eating protein (especially the branched-chain amino acid leucine) turn the mTOR switch on. The hormone insulin also turns on the mTOR building pathway. This effect of insulin should come as no surprise to readers of Strong Medicine (SM pages 107-108) as we discussed insulin as a hormone of growth and storage.

As Dan Cenidoza covered in his Strength after Sixty post, the anabolic pathways of building are crucial to grow and maintain muscle mass especially as we age. Not enough of “turning on” the mTOR switch can lead to sarcopenia and frailty in old age.

At the extreme end of the mTOR building pathway is cancer. By the simplest definition, cancer is uncontrolled cell growth. Recent science has shown that many cancer cells have abnormally high mTOR signaling, putting them is a perpetual state of growth. People with insulin resistance (SM p. 180) have higher levels of insulin in their bloodstream at all times which keeps the mTOR switch activated. Thus, it is no surprise that those with insulin resistance/diabetes are known to have increase risk of cancer.

We also now know that high levels of sustained mTOR activation can lead to accelerating aging in many species, including humans. With this information in mind, it becomes evident that getting the proper “dose” of mTOR activation is key.

We need enough “turning on” the mTOR building (growth) switch to prevent the loss of muscle mass so crucial for healthy aging, but no so much that we accelerate the aging process and become at increased risk for diseases such as cancer.

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mTOR is always {ON} in our ever sicker/obese population of folks eating multiple small meals of mainly carbohydrate/sugar centric fare (AS THEY WERE ADVISED TO...)

This road to hell was paved with the "good intentions" of trying to avoid dietary fat/cholesterol...

"Different/radical" response (rethinking what we know about cancer...)

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Potential Tactics for Defeating Cancer — A Toolkit in 1,000 Words

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LINK

see the links at the bottom of the piece linked above (and listed below)

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There is a deluge of writing about cancer.

Below, I’ve suggested a top-10 list of articles as starting points. Some are for lay audiences, some are technical, but all are worth the time to read. Here you go:

Looking for articles to pass to your parents, or to read as a lay person? Read these, in this order:
1. Non-technical talk by Craig Thompson, Pres/CEO of Sloan-Kettering
2. Science piece written about cancer (for non-technical audience) by Gary Taubes

Have a little background and want the 80/20 analysis, the greatest bang for the buck? Read this:
3. Relatively non-technical review article on the Warburg Effect written by Vander Heiden, Thompson, and Cantley

Peaking on modafinil during a flight to Tokyo? Want to deep dive for a few hours? Here are three recommendations, in this order:
4. Detailed review article by Tom Seyfried
5. Review article on the role of carb restriction in the treatment and prevention of cancer
6. Talk given by author of above paper for those who prefer video

Want four bonus reads, all very good? As you wish:
7. Moderately technical review article by Shaw and Cantley
8. Clinical paper on the role of metformin in breast cancer by Ana Gonzalez-Angulo
9. Mouse study by Dom D’Agostino’s group examining role of ketogenic diet and hyperbaric oxygen on a very aggressive tumor model
10. Mechanistic study by Feinman and Fine assessing means by which acetoacetate (a ketone body) suppresses tumor growth in human cancer cell lines

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LINK
NY Times Article..

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An Old Idea, Revived:
Starve Cancer to Death
In the early 20th century, the German biochemist Otto Warburg
believed that tumors could be treated by disrupting their source
of energy. His idea was dismissed for decades — until now.

BY SAM APPLEMAY 12, 2016

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