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re: OT scientist- Does mdma disrupt the blood brain barrier?

Posted on 9/1/14 at 2:03 pm to
Posted by Boats n Hose
NOLA
Member since Apr 2011
37248 posts
Posted on 9/1/14 at 2:03 pm to
I don't know much about it. I just know it acts on serotonin receptors (I think, or maybe it causes the release of serotonin, but either way, serotonin), and I saw one small excerpt in a textbook from a study done on mice that were given something like double the recreational dose of MDMA and it caused a change in amount of neurons/synapses in I forget what area of the brain that was still observed like 5 years out, so it appeared permanent. No changes in brain function were found related to the damage though.

I could google and get some more info, but I'm lazy, do it yourself.
Posted by rbWarEagle
Member since Nov 2009
49999 posts
Posted on 9/1/14 at 2:09 pm to
It causes the serotonin vesicles to release an overly large amount into the synapse.
Posted by mailman
Houston
Member since Jul 2009
6143 posts
Posted on 9/1/14 at 2:10 pm to
quote:

Boats n Hose




quote:

a study done on mice that were given something like double the recreational dose of MDMA


Well that's actually my point, those studies never test average doses and probably test it on the mice several times a week. No one I would think takes it that much.

This post was edited on 9/1/14 at 2:11 pm
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