re: The delicate dance of whether or not to take cold medicine

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Mucinex

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The wonder of marketing and manipulating the FDA.

Guaifenesin has been around since the 1930s. Originally approved by the FDA in 1952. Whether intentional or not, I can't say but Adams Respiratory managed to gain sole control of the time-released market, hence Mucinex cornoring the market despite not being the first guys out there by any stretch.

https://en.wikipedia.org/wiki/Guaifenesin

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In the US, guaifenesin was first approved by the Food and Drug Administration (FDA) in 1952. Although previously deemed "Generally Regarded as Safe" in its original approval, the drug received a New Drug Application for the extended-release version, which received approval on 12 July 2002. Because of this, the FDA then issued letters to other manufacturers of timed-release guaifenesin to stop marketing their unapproved versions, leaving Adams Respiratory Therapeutics in control of the market. In 2007, Adams was acquired by Reckitt Benckiser. The drug is now sold over-the-counter by many companies, alone and in combination.

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