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Started By
Message
Latest Covid19 study release: Needs Peer Review
Posted on 7/4/20 at 3:00 pm
Posted on 7/4/20 at 3:00 pm
LINK
Objective: To describe outcomes of patients with coronavirus disease 2019 (COVID-19) in the outpatient setting after early treatment with zinc, low dose hydroxychloroquine, and azithromycin (the triple therapy) dependent on risk stratification. Design: Retrospective case series study. Setting: General practice. Participants: 141 COVID-19 patients with laboratory confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in the year 2020. .....
One patient (0.7%) died in the treatment group versus 13 patients (3.5%) in the untreated group (odds ratio 0.2, 95% CI 0.03-1.5; p=0.16). There were no cardiac side effects. Conclusions: Risk stratification-based treatment of COVID-19 outpatients as early as possible after symptom onset with the used triple therapy, including the combination of zinc with low dose hydroxychloroquine, was associated with significantly less hospitalizations and 5 times less all-cause deaths.
Objective: To describe outcomes of patients with coronavirus disease 2019 (COVID-19) in the outpatient setting after early treatment with zinc, low dose hydroxychloroquine, and azithromycin (the triple therapy) dependent on risk stratification. Design: Retrospective case series study. Setting: General practice. Participants: 141 COVID-19 patients with laboratory confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in the year 2020. .....
One patient (0.7%) died in the treatment group versus 13 patients (3.5%) in the untreated group (odds ratio 0.2, 95% CI 0.03-1.5; p=0.16). There were no cardiac side effects. Conclusions: Risk stratification-based treatment of COVID-19 outpatients as early as possible after symptom onset with the used triple therapy, including the combination of zinc with low dose hydroxychloroquine, was associated with significantly less hospitalizations and 5 times less all-cause deaths.
3
Posted on 7/4/20 at 3:02 pm to cusoonkpd
Vladimir Zelenko involved in study.
Posted on 7/4/20 at 3:02 pm to cusoonkpd
quote:
p=0.16
Thats not good
Posted on 7/4/20 at 3:05 pm to Cosmo
Doesn't make sense to have a 95% CI that doesn't include 0, but a p-value that high?
NM, the 95% CI of the odds ratio includes 1. Was thinking about it in terms of linear estimates.
NM, the 95% CI of the odds ratio includes 1. Was thinking about it in terms of linear estimates.
This post was edited on 7/4/20 at 3:11 pm
Posted on 7/4/20 at 3:21 pm to Cosmo
That’s just deaths.
Difference in risk of hospitalization was statistically significantly different.
Difference in risk of hospitalization was statistically significantly different.
This post was edited on 7/4/20 at 3:22 pm
Posted on 7/4/20 at 3:44 pm to cusoonkpd
Trump’s fault.
Posted on 7/4/20 at 4:03 pm to Tiguar
quote:What was the effect size?
Difference in risk of hospitalization was statistically significantly different.
NM. I need to read better befor asking questions. .16 odds ratio, with a 95% CI of .06 to .5.
This post was edited on 7/4/20 at 4:06 pm
Posted on 7/4/20 at 4:10 pm to Gravitiger
I’d imagine there would have been a statistical significance with deaths with 100-150 more patients in each group
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