re: Which human being has made the biggest impact on human history?

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Yes, unquestionably. He has lighted the way to eternal life for billions

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I prefer to look at the glass as half-full and say that he has damned untold billions to eternal hellfire for pissing him off.

Either way, very influential. Not quite as influential as Judas, who told the Romans where to find the dude but a close second.