Have owned several snakes through the years, Ball pythons are fairly tame. I would suggest not feeding them live food, also NEVER feed them in their cage. Go to wal mart and get a Rubber maid container and feed them in there.
This way they do not associate the opening of their cage with food and when they get in the rubber maid container they will be ready to eat. They can be a little picky eaters when they are younger, just be patient.
Mist the cage regularly, provide plenty of heat. Also bring them outside on warm days, Sunlight is good for them.