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re: Has there been no SIGNIFICANT medical breakthroughs......

Posted on 6/2/15 at 1:48 pm to
Posted by TheCaterpillar
Member since Jan 2004
76774 posts
Posted on 6/2/15 at 1:48 pm to
quote:

Apologies if I seemed to overstate. I'm more privvy to the latest happenings with it, so I feel pretty confident and excited based on what's going on right now.


No offense, but every damn year there is a new thing that really excites people. There is crazy excitement over the process of fighting cancer with other diseases that are genetically modified too.

Cancer always finds a way to adapt and win. It sucks.
Posted by buckeye_vol
Member since Jul 2014
35239 posts
Posted on 6/2/15 at 1:48 pm to
quote:

Apologies if I seemed to overstate. I'm more privvy to the latest happenings with it, so I feel pretty confident and excited based on what's going on right now. The funding is all in place, as well, but of course they're always taking more investors since more money equates to their ability to hire more people for quickened processes.
No big deal. And no fault getting excited about something potentially great. I hope it is something great. I just think for the rest of us have to skeptic of everything. There have been too many miracle cures that have been oversold, and not just in regards to diseases.
Posted by tigerbandpiccolo
Member since Oct 2005
49284 posts
Posted on 6/2/15 at 1:53 pm to
I would encourage you to read the process. Targeted Osmotic Lysis: LINK

They've been working on this for years. Very basic cellular function and probably the least complicated treatment out there. Outpatient surgical procedure.
Posted by TheCaterpillar
Member since Jan 2004
76774 posts
Posted on 6/2/15 at 1:58 pm to
Picc that's cool. It really is. And I hope it works.

It's just that I have heard so many people tell me about new breakthrough treatments so many times. I am ruined in terms of optimism.
Posted by Grassy1
Member since Oct 2009
6256 posts
Posted on 6/2/15 at 2:02 pm to
I take a pill every day that keeps me from having leukemia.

Its worked for 4.5 years so far.

No such thing prior to 2000.
Posted by tigerbandpiccolo
Member since Oct 2005
49284 posts
Posted on 6/2/15 at 2:19 pm to
Understand, I feel the same way about most things.

I have nothing to do with any of it other than marriage. Husband helped his dad in the lab each summer in HS and college so he has a lot of emotional investment. Cheers
Posted by flyAU
Scottsdale
Member since Dec 2010
24851 posts
Posted on 6/2/15 at 2:19 pm to
quote:


Yeah, I'm cynical. But the average cancer patient is worth $400,000. Cancer foundations raise millions and millions of dollars, with very little actually going to research. A cure for cancer today would end the gravy train for a lot of folks.


you do realize that "cancer" is a very broad terminology right? hell even saying "breast cancer" is a huge scope. We are now in a new phase of health care where we have specific treatments for specific types of cancers. To say there is a conspiracy to make people keep paying for more treatments instead of curing is indeed a cynical mindset and a naive one.
Posted by retired trucker
midwest
Member since Feb 2015
5093 posts
Posted on 6/2/15 at 2:36 pm to
quote:

billions spent this doesn't seem to add up somehow.


sure does add up.

the answer was part of the question

billions spent!!!! there is no money in cures daddio...no money in cures....
just keep giving the BILLIONS, that's all they want is your money....get it?!
sorry you were the last to know.....
This post was edited on 6/2/15 at 3:12 pm
Posted by flyAU
Scottsdale
Member since Dec 2010
24851 posts
Posted on 6/2/15 at 3:15 pm to
Wow the general public needs some education on the research side of the medical field.

What good is a dead patient? If what think is happening is actually happening then we would have near zero mortality rate in cancer patients, but we found a way to have them keep living through maintenace. That is not the case. We are attacking the most aggressive and most previlant types of cancers first. Breast cancers and lung. We have specific treatments at this point that we know if they have specific markers, we know that a specific drug will fight the cancer instead of the shotgun approach.

My question for the consipracy theorists, who are the ones that are holding back these cures in your mind? Medical companies? Hospitals? Universitites? Insurance companies? Politicians?

The answer is, no one is.
Posted by Hopeful Doc
Member since Sep 2010
14965 posts
Posted on 6/2/15 at 4:13 pm to
quote:

My question for the consipracy theorists,


remains for them to form a logical explanation for the Gleevec (imatinib) debacle. Drug cures CML (one type of leukemia) caused by a specific translocation of a gene from one chromosome to another. It also costs thousands of dollars. The company is making money. People are being cured of CML.


Here's the kicker: not all CML is caused by the "Philadelphia" chromosome as described above, but the majority is. When talking about the four types of leukemia, there are even more subsets of each type (the disease is named after the clinical picture, not the reason it happens in this case), requiring different treatments, because they're different things with different causes.


Also, to think that Gleevec, specifically, isn't a medical breakthrough is simply a disagreement on terms of what a major medical breakthrough is that, if you do not agree with, we simply don't have enough common ground for discussion on the matter.
Posted by guedeaux
Tardis
Member since Jan 2008
13611 posts
Posted on 6/2/15 at 5:34 pm to
So only cures are significant? You are clearly and significantly ignorant in several subjects.
Posted by Weaver
Madisonville, LA
Member since Nov 2005
27722 posts
Posted on 6/2/15 at 5:49 pm to
Open heart surgery anyone
Posted by buckeye_vol
Member since Jul 2014
35239 posts
Posted on 6/2/15 at 6:04 pm to
quote:

So only cures are significant? You are clearly and significantly ignorant in several subjects.
It seems like even moreso than cures, he is weighting breakthrough by their headline exposure.
Posted by Rebel
Graceland
Member since Jan 2005
131420 posts
Posted on 6/2/15 at 6:06 pm to
Lulz. GCS alter.
Posted by UltimaParadox
Huntsville
Member since Nov 2008
40861 posts
Posted on 6/2/15 at 6:41 pm to
As a Gilead investor it is well known that hepatitis c has been cured.
Posted by yankeeundercover
Buffalo, NY
Member since Jan 2010
36373 posts
Posted on 6/2/15 at 6:47 pm to
There have been some INCREDIBLE breakthroughs in the world of prosthetics... There's a really good TED talk about the latest and greatest from a private company.
Posted by slacker130
Your mom
Member since Jul 2010
8019 posts
Posted on 6/2/15 at 6:50 pm to
quote:

Has there been no SIGNIFICANT medical breakthroughs since 1955 when the cure for polio was announced?


Bruce Jenner has a vagina. That's gotta count for something.
Posted by BBONDS25
Member since Mar 2008
48439 posts
Posted on 6/2/15 at 6:51 pm to
The Salk institute has made many breakthroughs. There is also the human genome project and many more...
Posted by Tiger in Austin
Austin,TX
Member since Sep 2003
1755 posts
Posted on 6/2/15 at 7:43 pm to
Posted by Hopeful Doc
Member since Sep 2010
14965 posts
Posted on 6/2/15 at 9:03 pm to
While very interesting, I'm not sure I'd put terribly much faith into that HIV cure. One of its major problems is how terrible it is at replicating itself. It does it fast, and with a ton of errors. There are about 1,000 base pairs in the viral genome. Its rate of reproduction and error are such that every single error (1,000 possible) occurs in a 24 hour period at least once. Moreover, about half of the double recombinants (base 1+2, 18+920, etc) occur in that same time frame. The breeding ground for resistance is quite high. Should every single virus be expressed and attacked by triple therapy at once, it's possible. But that's kind of a long shot. And it takes but one, single viral particle that is resistant to three drugs to become the new, dominant strain, rendering the three other therapies inefficient.


It's a screwy little bug. It would take some careful genome mapping to get the "attack" phase right.
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