Hollywood and "age"/suspension of disbelief

Hollywood has long played fast and loose with casting. The classic example is Grease, with most of the principal cast pushing 30 or older, with Travolta kind of being the "kid" and playing a HS senior in his early 20s.

Breakfast Club is maybe a touch better, overall, with Ringwald and AMH being about perfect for HS seniors, Estevez and Sheedy early 20s and really only Judd Nelson standing out for being too old for the part.

Sometimes age is kind of an obvious issue with pairings (either a romantic situation or familial relationship) that don't quite fit. Anne Bancroft (Mrs. Robinson) was less than 6 years older than Dustin Hoffman in The Graduate. Now, she was playing older (obviously supposed to be in her 40s) and was only 9 years older than Katherine Ross who played her daughter in the same film.

Similarly, in the HBO series Succession, Brian Cox plays older, explicitly, as they have his character's 80th birthday celebration, despite Cox still being in his mid-70s. Alan Ruck plays his oldest son, despite being just 10 years and 1 month younger. Of course, Ruck could also be in this list for Ferris Bueller, where he was almost 30 playing a HS senior.

In Sanford and Son, Red Foxx and Demond Wilson were about 24 years apart in age, so that part wasn't too bad, but Foxx was still in his 40s when he started that role, playing a character roughly 15 years older (without prosthetics or any significant age enhancements, other than hair and wardrobe).

(What triggered this was a discussion about the Penny Benjamin character from the Top Gun series. Obviously, folks do not want to consider that character the same age as the actress (Jennifer Connelly) in the sequel, because that would have entailed an *ahem* "uncomfortable" conclusion about the events immediately prior to the original film, in which the character is not portrayed, but only referenced.)

Obviously, I'm excluding the age issues where it is explicitly addressed and part of the drama (or comedy) - e.g. Jodie Foster in Taxi Driver, or the May-December situation in Modern Family.

On a related note, Hollywood tends to pair older men with younger women in situations relatively routinely. A rare reversal of this was The Jeffersons. Isabel Sanford (Weezy) was 21 years older than Sherman Hemsley (George), although obviously, she was playing a younger character than her age and he was playing older (both credibly, IMHO).

Obviously, going back to Charlie Chaplin, their IRL relationships often result in eyebrow raising age differences.

Any other age-related casting or Hollywood (Leo would be good fodder, there, right?) age gaps/discrepancies to consider?