Sounds like there will never be a better time for this type of opportunity. You can always come back home and work locally, but the opportunity for the increased income/networking/travel may never again be something you are interested in/can justify.
My job required required a lot of regional travel at first (apprx 125 nights first year), but that has slowed down significantly, due mainly to increased need locally. I could not have maintained that pace for much longer, especially once we started having children. The travel was tough but had a lot of benefits. I have a ton of loyalty points with Hilton and Marriott and a huge number of Delta sky miles. This has allowed my family to go wherever, whenever. I also "paid my dues" and earned a lot of brownie points with my superiors, allowing for several promotions and raises since then.
I say go for it. Good luck.
This post was edited on 5/10 at 9:31 am