I'm from Destin. The prices are a great time to buy in the area. If you are able to manage it during the year, then I'd say yes (and some property mgmt companies are very fair and allow enough income for you to cover most mortgage costs).
If you can get the financing and manage the upkeep whether through a property management company then I'd say YOLO.
The big questions you should be asking is who is your target tenant. Destin get's pretty sparce in the off-season, and if you have mid-term off season leases, then your in good shape.
This post was edited on 4/3 at 11:22 pm