This might not be such a horrible thing. Brees tends to focus too much on him at times. It would be a good chance to work on some of our other receivers and get the run game going.
It's never a good thing in the NFL when one of your best players is out. That said, I agree that it was getting to the point where it seemed as if 80% of the passes were going to either Graham or Sproles. I understand that those guys present massive mis-matches for opposing defenses, but when this offense is clicking, the ball is being spread around to everybody. If a defense is making a concerted effort to shutdown Graham, then there are other guys who should be open.