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Just had my annual physical and got my blood panel back

Posted on 4/27/23 at 7:22 am
Posted by dallastiger55
Jennings, LA
Member since Jan 2010
27723 posts
Posted on 4/27/23 at 7:22 am
I'm 42, work out 6x a week, 5'11 165 and lean. I've been running high on cholesterol the last two years out of the blue. I do have family history and my dad is 72 and has heart disease and had quad bypass surgery at 38. I'll also add I'm under care of a cardiologist because I had a 1200 calcium score at 40. Did a heart Cath and the arteries looked great (Dr. said i had arteries of a 20-year-old). Very good Co2 level and resting heart rate of 42.

Last year I had
Total Cholesterol- 180
HDL- 61
LDL- 115
Tryg- 61
Non-HDL- 115

From Yesterday:
Total Cholesterol- 188
HDL- 57
LDL- 118
Tryg- 59
Non-HDL- 131

I really cut back on things in Jan and cut out candy and any heavy sat fat sweets. Swapped out all my sugary protein bars for very low ones.

Very light drinker, don't smoke, eat very healthy 90% of the time. I'm really bummed about this because I've made an effort the last 6 months to lowering LDL, cut out bad foods, read books, more sleep, more water, less drinking, Yoga, etc.

Any feedback is appreciated.


Posted by guedeaux
Tardis
Member since Jan 2008
13611 posts
Posted on 4/27/23 at 8:06 am to
Your cardiologist should have told you that cholesterol is controlled more by genetics than diet, in non-obese individuals. These easily could be your genetic baseline numbers.

If all other tests show that your heart is healthy and you feel healthy, then keep on keepin'on, bro.
Posted by dallastiger55
Jennings, LA
Member since Jan 2010
27723 posts
Posted on 4/27/23 at 8:35 am to
He’s said that before, yes. Especially after my cath.

Yesterday was with my GP and I guess I was bummed because I was hoping, eating better and cutting out food would at least make some difference

Did those levels look bad enough to start a statin?
This post was edited on 4/27/23 at 8:35 am
Posted by Motorboat
At the camp
Member since Oct 2007
22683 posts
Posted on 4/27/23 at 8:51 am to
I don't believe the cholesterol hype. Big pharma, yada yada
Posted by whiskey over ice
Member since Sep 2020
3263 posts
Posted on 4/27/23 at 9:06 am to
How much weight have you lost this year? Could be that the mobilizing of stored body fat into your bloodstream is increasing your cholesterol levels.

Disclaimer: not a doctor
Posted by OysterPoBoy
City of St. George
Member since Jul 2013
35151 posts
Posted on 4/27/23 at 9:14 am to
Have you listened to Peter Attia? I especially like when he's on Huberman Lab. He has a family history of early heart attacks and really gets into what markers you should be looking for and what meds you may want to look at.
Posted by BigPerm30
Member since Aug 2011
25939 posts
Posted on 4/27/23 at 9:45 am to
quote:

Have you listened to Peter Attia? I especially like when he's on Huberman Lab. He has a family history of early heart attacks and really gets into what markers you should be looking for and what meds you may want to look at.


Loved that podcast. My understanding that ApoB is the real indicator yet no one tests for that routinely. In my next physical I’m asking for that test.
Posted by OysterPoBoy
City of St. George
Member since Jul 2013
35151 posts
Posted on 4/27/23 at 9:58 am to
quote:

My understanding that ApoB is the real indicator yet no one tests for that routinely. In my next physical I’m asking for that test.


He's big on ApoB. I think he said when you test LDL now you don't really get how much LDL you have only what amount of cholesterol is in your LDL cells (or something like that). ApoB shows you what % of your cholesterol is LDL (I think).

Some people are born with a very low ApoB and those people never have heart disease issues. He wants his clients to get their ApoB as low as possible.
Posted by lsu777
Lake Charles
Member since Jan 2004
31112 posts
Posted on 4/27/23 at 10:03 am to
try this protocol

take Nattokinase at 12-14k FU daily (6-8 caps per day)

citrus bergamot- 3-4000mg/day (6-8 caps/day)

Krill oil- 6000mg high quality daily

8oz of 100% Pomegranate Juice not from concentrate daily

glucosevantage xt by SNS LINK - 1 cap with every meal


do the above and start lifting weights, like a real program. stop doing a ton of cardio just do the above and do something like ppsa grasshopper then other ppsa programs. do this for 16 weeks and make sure you get 8 hours sleep every night and get back to us on the numbers.

i can promise they will be significantly better and so will your calcium score.

Posted by BigPerm30
Member since Aug 2011
25939 posts
Posted on 4/27/23 at 10:03 am to
quote:

He's big on ApoB. I think he said when you test LDL now you don't really get how much LDL you have only what amount of cholesterol is in your LDL cells (or something like that). ApoB shows you what % of your cholesterol is LDL (I think).


This was my takeaway as well. Those two guys are so fricking smart I’ve got to rewind that shite multiple times and sometimes I still don’t understand.
Posted by OysterPoBoy
City of St. George
Member since Jul 2013
35151 posts
Posted on 4/27/23 at 10:05 am to
quote:

Those two guys are so fricking smart I’ve got to rewind that shite multiple times and sometimes I still don’t understand


I usually listen while I'm driving and wish I was able to take notes. The ones with Andy Galpin are incredible also.
Posted by TAMU-93
Sachse, TX
Member since Oct 2012
898 posts
Posted on 4/27/23 at 10:09 am to
quote:

I had a 1200 calcium score at 40.


Is that your coronary artery calcium score?
Posted by JustinTI
New Orleans
Member since Nov 2006
199 posts
Posted on 4/27/23 at 10:27 am to
OP, I'm a little younger than you, but in the same general boat. Eat very clean, exercise, and am pretty lean. Standard lipid panels (which as noted above measure the amount of cholesterol in a lipid particle) show my numbers as very high. I did an advanced panel (# of apo b particles, Lp(a), etc.), and the results were better - but mixed...Still working through it, as I do think there is some benefit to a statin to some groups, but not to the level of dishing them out like candy as many doctors do.

If you have not had an advanced lipid panel, I'd suggest getting one. I tried to get a doctor to order it, but most are ignorant on recent literature and do not understand them. In the end, it was cheaper and easier to just order myself. Below is the link to a good set of labs for $150. It is definitely worth getting your Lp(a) measured, as that is not correlated to any results of a standard lipid panel (whereas there is usually some correlation to apo-b particle number and non-hdl cholesterol measurements). Attia/the cardiac experts he has on have called it the silent killer, and it is completely genetic and largely unmodifiable by current medications.

LINK
Posted by JustinTI
New Orleans
Member since Nov 2006
199 posts
Posted on 4/27/23 at 10:35 am to
quote:

ApoB shows you what % of your cholesterol is LDL


Standard cholesterol labs measure the amount of cholesterol carried within a lipid particle. The scientific name of a non-HDL lipid particle is the Apolipoprotein B particle ("Apo B"). When you get an Apo B measurement you are getting a measurement of the amount of the non-HDL cholesterol carrying particles instead of the amount of cholesterol contained therein. There is some correlation between the standard lipid panel measurement and an Apo B reading, but it is not 100% and varies.

Disclaimer, I am not a MD. This is just my understanding from doing plenty of research on the issue.
Posted by dallastiger55
Jennings, LA
Member since Jan 2010
27723 posts
Posted on 4/27/23 at 11:31 am to
Dang so my Non HDL is even worse?

Any of y’all done the mail at home blood tests?
Posted by OysterPoBoy
City of St. George
Member since Jul 2013
35151 posts
Posted on 4/27/23 at 3:34 pm to
quote:

it is completely genetic and largely unmodifiable by current medications.


Maybe I misunderstood what I heard but I thought it was treatable. I’ll have to go have another listen.
Posted by Blutarsky
112th Congress
Member since Jan 2004
9609 posts
Posted on 4/27/23 at 4:14 pm to
It’s a struggle for me to get my HDL levels up.

My last blood panel

Cholesterol: 156
Tri: 75
HDL: 38
LDL: 103
Non-HDL: 118
Posted by JustinTI
New Orleans
Member since Nov 2006
199 posts
Posted on 4/27/23 at 4:54 pm to
quote:

Maybe I misunderstood what I heard but I thought it was treatable. I’ll have to go have another listen.


PCSK9 inhibitors can reduce Lp(a), but those are expensive, require injections, and are not widely used. I believe there are some medications in clinical trials that have shown promise to lower Lp(a). Statins have minimal (if any) effect on Lp(a).
Posted by OysterPoBoy
City of St. George
Member since Jul 2013
35151 posts
Posted on 4/27/23 at 5:18 pm to
quote:

PCSK9 inhibitors can reduce Lp(a), but those are expensive, require injections, and are not widely used


That’s probably what Attia is using then.
Posted by dallastiger55
Jennings, LA
Member since Jan 2010
27723 posts
Posted on 4/27/23 at 6:04 pm to
Ok so if i want to look at getting a test, should i do Apo 1a or Apo B? Or both?

Whats the difference?
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