If people aren’t eating on GLP-1 drugs how R they not weak/tired? Body using fat for fuel?

what? Not eating does not = eating in a deficit.

It’s just an appetite suppressant. And that is just a previously unknown side effect.

You aren’t hungry so you aren’t cranky. You start losing weight and immediately feel better.

Unless you start having gastric issues. Retaining food longer than the body intended is something that is really fairly new. Maybe it ends up fine? Maybe we’ve just scratched the surface on issues. Will take time to find out.

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Was there a study that showed people on GLP-1 drugs had proportionate loss in muscle mass in comparison to fat loss?

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Correct. It’s why if you have a decent doctor they’ll tell you that you need to consider weight training as you lose the weight. My SO lost some muscle but was able to curb that side effect quite a bit by lifting with it.

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Any time you have a calorie deficit without high protein diet and resistance training you’ll lose muscle, not just with GLPs. GLPs just tend to cause a higher deficit.

I was a dumbass my first 5-6 months on GLPs and lost quite a bit of muscle and strength. But after getting to a more comfortable weight, I’m now in the gym 4-5x a week and re couping my losses. It’s coming back quickly so was definitely worth it for the weight loss I achieved.

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Yeah, you'll see really heavy guys who haven't ever lifted consistently do linear progression programs and gain strength VERY quickly while also losing a ton of weight if the diet and protein intake is right. Its really a cheat code.

But with that said, its also extremely difficult to have the willpower to do that. Like Joe Rogan said on an episode a few years ago to a guest who couldn't understand how people could get so out of shape... when you're working a job, have a family, a house to take care of, pets, plus want some time to enjoy for yourself, its really taxing on people to work out. Just getting through the day can take all the energy they have. And thats just trying to get them to work out at all, much less commit to something like a LP plan.

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But with that said, its also extremely difficult to have the willpower to do that. Like Joe Rogan said on an episode a few years ago to a guest who couldn't understand how people could get so out of shape... when you're working a job, have a family, a house to take care of, pets, plus want some time to enjoy for yourself, its really taxing on people to work out. Just getting through the day can take all the energy they have. And thats just trying to get them to work out at all, much less commit to something like a LP plan.

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Yeah, it can be very hard. I have a very flexible WFH job and I can go basically anytime as long as I don't have anything pressing or a meeting.. but i often get so wrapped up in what im doing or dealing with stuff that, if I don't block off my calendar and make it a non-negotiable priority, it's very hard to get even 3x a week. Even with just equipment at my house, other things pop up and make it hard to prioritize the time.

For me, classes make a difference since it is like another appointment to attend, can't really push it around or move it for people. But not everyone can or wants to pay that kind of money.