Will the 420 fit in back of an F-150 standard bed with tailgate up?
It should, I have an 08 420, and it fit in the back of my Silverado 1500 step side, if you have a tool box though it will not. Since I put the tool box in, I bought the LA Guard Dog, mounts to the trailer hitch of the truck and the ball of the wheeler, and it works great. Takes about as much time as using straps, but way stronger.
I run the ITP mudlites, they are a great tire.
The 420's are so nimble, you will love it. But it you put the lift on you will take some of that away. Buddy has the same bike I have with a lift, and I def prefer mine without. Guess it just depends on what you like though.