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Wow. Brazil Study Shows *early* HCQ significantly decreases hospitalization rates
Posted on 4/17/20 at 3:18 pm
Posted on 4/17/20 at 3:18 pm
(n=636) with a p<0.001; 412 received HCQ/Azithromycin and the control group 224 did not receive medication.
Hospitalization Rate in HCQ/Z pack Group: 1.9%
Hospitalization Rate in Control: 5.4%
Those who were treated in the first 7 days of symptoms: 1.17%
Those who were treated in the after the first 7 days of symptoms: 3.2%
Link to Preprint
Hospitalization Rate in HCQ/Z pack Group: 1.9%
Hospitalization Rate in Control: 5.4%
Those who were treated in the first 7 days of symptoms: 1.17%
Those who were treated in the after the first 7 days of symptoms: 3.2%
Link to Preprint
Posted on 4/17/20 at 3:31 pm to OKtiger
yep, brazil and india is where i want to get my cutting edge healthcare from.
Posted on 4/17/20 at 3:31 pm to dandyjohn
quote:
yep, brazil and india is where i want to get my cutting edge healthcare from.
Other countries have found the same.
Posted on 4/17/20 at 3:34 pm to OKtiger
Of course you must disbelieve this - if Trump says it "shows promise" it must be bad.
Posted on 4/17/20 at 3:35 pm to OKtiger
Instead of money, we need to send this to everyone.
Posted on 4/17/20 at 3:35 pm to dandyjohn
quote:
yep, brazil and india is where i want to get my cutting edge healthcare from
Cutting edge, using medications off label..
Posted on 4/17/20 at 3:36 pm to OKtiger
this is actually a pretty big deal if valid
closest thing we have to a real trial since this shite started and they found a statistical difference and even gave us a NNT.
closest thing we have to a real trial since this shite started and they found a statistical difference and even gave us a NNT.
Posted on 4/17/20 at 3:36 pm to dandyjohn
quote:
yep, brazil and india is where i want to get my cutting edge healthcare from.
I know that one of the leading hospitals in the country is using it as first recommendation (5 days), so there has to be something to it.
This post was edited on 4/17/20 at 3:37 pm
Posted on 4/17/20 at 3:37 pm to Tiguar
There are ongoing clinical trials.
Posted on 4/17/20 at 3:41 pm to blueridgeTiger
quote:Well, the downvotes show that some people hold that view.
Of course you must disbelieve this - if Trump says it "shows promise" it must be bad.
Rather people die than have Trump proven correct.
Posted on 4/17/20 at 3:41 pm to dandyjohn
quote:
yep, brazil and india is where i want to get my cutting edge healthcare from.
I think it's ironic because there was a Brazil trial that everyone was referencing a couple days ago showing HCQ's "ineffectiveness and safety hazards" when the scientists were giving 1200 mg doses to patients who were effectively on their death bed.
Everyone wanted to believe that trial
Posted on 4/17/20 at 3:42 pm to OKtiger
Hydroxychloroquine fails first meaningful RCT - PulmCrit
quote:
- This is the first multi-center RCT investigating the use of hydroxychloroquine for COVID-19. 150 adult patients hospitalized with COVID-19 were randomized in an open-label, non-blinded fashion.
- Hydroxychloroquine had no effect on the duration of viral detection (despite the use of high doses and a prolonged 2-3 week course).
- Clinically, there was no discernible beneficial effect from hydroxychloroquine. However, hydroxychloroquine did appear to cause some side-effects (most notably diarrhea).
- Further studies on hydroxychloroquine will likely be emerging soon. For now, the best available evidence does not support the use of hydroxychloroquine in COVID-19.
- Given evidence of harm without evidence of benefit, it seems prudent to restrict the use of hydroxychloroquine to randomized controlled studies for the time being.
Posted on 4/17/20 at 3:43 pm to dandyjohn
quote:
yep, brazil and india is where i want to get my cutting edge healthcare from.
Countries like those tend to have the most experience with lethal communicable diseases due to their tropical nature, lower standard of living, and high numbers of the poor living in tight quarters.
Posted on 4/17/20 at 3:44 pm to cwil177
quote:
Hydroxychloroquine fails first meaningful RCT - PulmCrit
quote:
Treatment was initiated late, an average of 16-17 days after disease onset:
Libs furiously downvoting anything that might be positive
This post was edited on 4/17/20 at 3:46 pm
Posted on 4/17/20 at 3:44 pm to OKtiger
Also, this is a study on patients who never got a COVID test
Posted on 4/17/20 at 3:45 pm to Scruffy
HCQ should have been given anybody and everybody the first day of symptoms at the first onset of this crap. And masks should have been mandated as soon as it became known to be in the USA. These 2 things would have held back this crap and it would be totally done much quicker than it will be now.
Of course, Democrats would have screamed because there would not be a crisis now.
Of course, Democrats would have screamed because there would not be a crisis now.
Posted on 4/17/20 at 3:45 pm to xxTIMMYxx
on going doesnt help me much RIGHT NOW.
Posted on 4/17/20 at 3:48 pm to LNCHBOX
quote:
Treatment was initiated late, an average of 16-17 days after disease onset:
Definitely a valid criticism! Still the best data we have so far.
quote:
Adverse events were found in 30% of patients treated with hydroxychloroquine, versus 9% of the control group. Although not statistically significant, progression to severe disease occurred at a higher rate in patients receiving hydroxychloroquine.
We know there are harms, though.
quote:
Of course, it is possible that earlier use of hydroxychloroquine could be beneficial (e.g., perhaps at the first signs of illness on an out-patient basis). This is under investigation and additional data is likely to be forthcoming soon. Even if this does work in the outpatient clinic, it would probably have little impact on the management of these patients within the intensive care unit.
I would love to see a double blind, placebo controlled RCT on early administration of HCQ + zinc in patients getting hospitalized. I think this actually holds promise.
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