re: Johnson & Johnson 1 shot vaccine shows 66% efficacy, 85% v severe disease

quote:

---

Damn you are dumb

---

You are aware that studies have indicated possibly greater than 90% natural immunity from COVID, right?

This is based on the asymptomatic rates. If you don't have symptoms after contracting the virus you technically don't have COVID and are immune from it.

Nowhere did the vaccine efficacy studies take this into account. They only included people that were much more likely than average to already be asymptomatic (or immune) to COVID.

But please, continue to not do the research yourself and trust the media.

quote:

---

I have seen some Dr on twitter say that had Moderna or Pfizer done their trials at the height of infection like J&J their efficacy would be lower. A lot of Dr believe while still very effective the 90% plus numbers are likely not accurate.

---

From what I'm reading, Moderna and Pfizer did their trials before the new South African and Brazil variants. Those are proving to be more evasive of the vaccine. I would think Moderna and Pfizer are more likely in the range of J&J now. Those are still pretty good numbers considering the flu shot is usually 40-60% effective.

quote:

---

I know it will take awhile to study but I am very interested to see what happens when vaccines are given to people who already have some natural immunity due to a previous infection.

---

Those individuals have a stronger immune response to the vaccine according to the personnel who have me my Covid-19 shot yesterday. Since the immune system is already primed it acts much like how others respond to the 2and dose.

quote:

---

The amateur scientist in me thinks it would boost efficiency but this area certainly isn't in my wheelhouse.

---

Regular exposure is what keeps the immune system primed to respond. So getting it, then getting the vaccine isn't hurting anyone.

Tier One
Pfizer
Moderna

Tier Two

Tier Three

Tier Four

Tier Fail
Johnson & Johnson

All the data really isn't true. Sure they have controlled all they can, however they have no idea people's resistance or reaction from Covid. We've seen that first hand without any input at all. Hell,I've witnessed it myself taking care of my son with Covid and none of us getting it. Even though there were plenty of opportunities especially right before he was positive and had symptoms.

Not sure how they can factor natural immunity into it. If they say they are 72% effective against moderate/severe disease, doesn't that sound about like where we are naturally without anything? I would say even a higher percentage than that naturally.

JNJ, PFE, and MRNA - all likely pretty similar efficacy when it's all said and done.

Consider this:

-Mean age of JNJ trial participants = 69.9
-Mean age of MRNA trial participants = 51.4
-Median age of PFE trial of participants = 52.0 - keep in mind this is median, not mean. Also, 57% of participants were below the age of 55.

Also to consider:

-JNJ trial - Black/Latino/Native American percent of total participants = 73%
-MRNA trial - B/L/NA percent of total = 35%
-PFE trial - B/L/NA percent of total = 37% (study did not report NA numbers)

Finally consider geography:

-JNJ trial - 15% of participants were from South Africa
-MRNA trial - no South African participants noted in study
-PFE trial - 2% of participants were from South Africa

JNJ trial also had a higher incidence of patients with comoridities than that of PFE and MRNA.

Bottom line. Comparing studies is comparing apples and oranges as it is in this instance.

PFE

MRNA

JNJ