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re: Humira for Psoriasis - Anyone taken it?

Posted on 1/14/16 at 2:08 pm to
Posted by Eurocat
Member since Apr 2004
15047 posts
Posted on 1/14/16 at 2:08 pm to
If you start with Otezla can you work backwards to Humira?
Posted by Jack Daniel
In the bottle
Member since Feb 2013
25469 posts
Posted on 1/14/16 at 2:09 pm to
No, I don't have leprosy
Posted by SportsGuyNOLA
New Orleans, LA
Member since May 2014
17027 posts
Posted on 1/14/16 at 2:13 pm to
quote:

If you start with Otezla can you work backwards to Humira?


I would assume so- but better to ask your derm.

I was on them both at the same time while transitioning from Humira to Otezla.
Posted by buffbraz
Member since Nov 2005
5673 posts
Posted on 1/14/16 at 2:17 pm to
quote:

If you start with Otezla can you work backwards to Humira?


You can be prescribed each at the same time or use one of the other for montherapy.

As far as the cancer risk, there is a statistically significant risk for leukemias and lymphomas albeit very small

quote:

In the controlled portions of 37 global Humira clinical trials in adult patients with RA, PsA, AS, CD, UC, Ps and HS, 2 lymphomas occurred among 7723 Humira-treated patients versus 1 among 4598 control-treated patients


...this per per the PI.
Posted by pioneerbasketball
Team Bunchie
Member since Oct 2005
132353 posts
Posted on 1/14/16 at 2:17 pm to
quote:

I would let someone hit me in the balls with a sledgehammer every two weeks if I knew it would get rid of the psoriasis.


Posted by usc6158
Member since Feb 2008
35351 posts
Posted on 1/14/16 at 2:17 pm to
quote:

You will get cancer eventually on Humira.

Have you tried diet modification?



I'm sure you think vaccines cause autism also
Posted by buffbraz
Member since Nov 2005
5673 posts
Posted on 1/14/16 at 2:28 pm to
quote:

You will get cancer eventually on Humira.


Not that it can't or will not happen, but we've prescribed hundreds of biologics over the past 8 years at our clinic and we've never had this issue. So in the real world, this rarely happens. On the flip side, not every patient that starts biologics has improvement. But the ones that do have significant improvement. Also, otezla is a lot easier to manage with a smaller side effect profile, but the efficacy is not as good.
Posted by LSUfan20005
Member since Sep 2012
8817 posts
Posted on 1/14/16 at 4:26 pm to
quote:

Have you tried diet modification?


Legit question. Have you?

Many people see at least some improvement from autoimmune conditions by modifying their diet.

It's at least worth a shot, right?

I'm not saying that you need to go the no-meds route, but you wouldn't take cholesterol meds without diet modification, would you?
Posted by GeauxTime9
Baton Rouge, La
Member since Dec 2010
6403 posts
Posted on 1/14/16 at 4:50 pm to
quote:

Have you tried diet modification?



No, i haven't tried any kind of diet modifications. Are you referring to some sort of gluten free diet? I have read some places that this can help. I just don't know if i could handle a gluten free diet, haha. I purchased the spray that was mentioned earlier in the thread. I will continue to do the light therapy, as that has worked in the past. I grew up getting tons of exercise by playing sports all through high school and college. So, i think i am going to try and get back into the gym thing and maybe see if that has a good effect on it. The only areas that it is very noticeable is on my legs. Overall my scalp has to be the worse and it creates dandruff x a million. Honestly, if i could just figure out how to cure the scalp, i could live with it on my body. Anyways, some of y'alls comments have been very helpful.
Posted by Cdawg
TigerFred's Living Room
Member since Sep 2003
59520 posts
Posted on 1/14/16 at 5:04 pm to
quote:

I just don't know if i could handle a gluten free diet, haha.

I had a client that had it real bad. He not only cut out gluten but also dairy and red meat. He just eats fish/chicken and fruit and vegetables. He even cut out beer and alcohol. I couldnt' do it but he says it has helped big time. But he also one of those granola type people that would also take natural supplements too. I did notice some improvement on him. He had it bad on his forehead to scalp but after the diet change, his complexion and skin looked better to me.
Posted by Remedy83
Central, LA
Member since Apr 2007
469 posts
Posted on 1/14/16 at 5:05 pm to
when I first started humira about 4 years ago it was a life changer, basically completely clearing up my skin 95%. However after a couple years my body got used to it and it didn't work as well so I switched... BIG MISTAKE ... switching to embryll brought back all of my horrible symptons and my entire body broke back out.. I am now back on humira and its slowly getting better. I recommend trying it and sticking with it, let me know if you have any questions
Posted by GeauxTime9
Baton Rouge, La
Member since Dec 2010
6403 posts
Posted on 1/14/16 at 5:09 pm to
quote:

when I first started humira about 4 years ago it was a life changer, basically completely clearing up my skin 95%. However after a couple years my body got used to it and it didn't work as well so I switched... BIG MISTAKE ... switching to embryll brought back all of my horrible symptons and my entire body broke back out.. I am now back on humira and its slowly getting better. I recommend trying it and sticking with it, let me know if you have any questions


This is good to know, i think i will give the topicals, exercise, and a little diet change a shot. If it doesn't seem to change at all, i will ask more about humira.
Posted by IonaTiger
The Commonwealth Of Virginia
Member since Mar 2006
33053 posts
Posted on 1/14/16 at 5:14 pm to
I did the creams and light chamber which worked for a while. Then I hit a wall. I was reluctant to try HUMIRA because I had a reaction to a drug after an angioplasty that shut down my immune system. HUMIRA suppresses the immune system, so I was a bit concerned.

Well, after a few years of being itchy and being in pain I decided, HUMIRA is either going to cure me or kill me. I gave it a try. I had to be tested before I started and still get tested every six months.

I started it in August 2013. Inside of three months a was 80% cleared. I still have a few patches on my legs that I use the creams on from time to time. As far as I am concerned, HUMIRA is a miracle drug. All drugs come with a risk, it was worth the risk for me.

Good luck.

Posted by TigerRagAndrew
Check my style out
Member since Aug 2004
7217 posts
Posted on 1/14/16 at 7:58 pm to
I posted that from familial experience. Sad thing is, it's the only drug that manages his symptoms so he still takes it even after having his entire cancerous kidney removed.

I will now go and cry myself to sleep due to being called an idiot by "dcw7g".
Posted by its1999
Member since Aug 2009
1039 posts
Posted on 1/14/16 at 8:12 pm to
So switching back to a former drug was possible for you? I take Remicade for a different auto immune disease, but am having more and more issues lately. During a previous appt, doc prescribed Humira, but my symptoms reversed after a regular Rem infusion. But with my remission failing, I'm hoping he'll recommend a booster dose of Rem rather than a switch to Humira. Just hate to exhaust all my drug options, and hate to give up on a drug that worked awesomely for 4 years.
Posted by wal marks
bee arrah
Member since Mar 2013
1115 posts
Posted on 1/14/16 at 8:24 pm to
People with autoimmune diseases tend to be more prone to certain types of cancer including lymphoma to start with. This is something that is rarely spoken of for some reason.

I have been on humira for severe psoriasis for a year now and that shite works wonders. Don't frick around with strep throat if you can help it. Turned my plaque psoriasis into erythrodermic psoriasis very quickly. Look it up. That is the most pain I have ever been in in my life. Good luck.
Posted by wal marks
bee arrah
Member since Mar 2013
1115 posts
Posted on 1/14/16 at 8:26 pm to
I have also tried the topicals and uv. shite works for a little while but not as well as a shot every week (enbrel) or every two weeks (humira)
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