re: Can anyone confirm some IF broscience with anecdotal evidence?

That is exactly why I didn’t list autophagy as a benefit to IF/Time Restricted Eating (“TRE”). As I look into it more and more, it seems that we need 16+ hours of fasting before it is triggered. This would obviously be a huge advantage of longer fasts as Dr Longo and many others have deduced. I am really interested in Dr Longo’s research on immune system turnover in mice after extended Fasting Mimicking diets. Essentially, after a prolonged fast of a few to five days, his studies in mice show that “malfunctioning” or overactive immune cells are turned over first via autophagy. Then, upon refeed, growth hormone levels skyrocket and their bodies use internally generated stem cells to create new, healthy immune cells. Obviously a dumbed down version as there are a lot that goes into “immune cells”, but very interesting. Next steps are to see if this occurs in humans as well.