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re: Pancreatic cancer - The saga continues - RIP lovelsu

Posted on 7/24/18 at 11:25 am to
Posted by RadioactiveTiger
Chernobyl
Member since Aug 2007
166 posts
Posted on 7/24/18 at 11:25 am to
Your tumors may not show up on a regular PET scan as the study depends on the accumulation of FDG - a radioactive sugar conjugate that normally accumulates in rapidly dividing cells. The study in Germany uses a "DOTA-conjugated NTR1 antagonist 3BP-227" for imaging and therapy - a protein that is often over expressed in pancreatic cancer.

This research is the basis of targeted therapy where we image you with a small dose of a new type drug and if you uptake we give you a larger therapeutic one. It may or may not be an option but I thought it would be worthwhile to mention.
Posted by G Vice
Lafayette, LA
Member since Dec 2006
12925 posts
Posted on 7/24/18 at 11:40 am to
The depth and breadth of this board never ceases to amaze.
Posted by Parallax
Member since Feb 2016
1450 posts
Posted on 7/24/18 at 11:41 am to
Dotatate PETs are for neuroendocrine tumors.

She likely has pancreatic adenocarcinoma, which is far more common than a neuroendocrine tumor and for which Lutathera/Dotatate PET has no role.
This post was edited on 7/24/18 at 11:44 am
Posted by lovelsu
Crowley, LA
Member since Jan 2007
780 posts
Posted on 7/24/18 at 11:52 am to
quote:

This research is the basis of targeted therapy where we image you with a small dose of a new type drug and if you uptake we give you a larger therapeutic one.


I will forward the link to my Oncologist. Do you know if this is being done anywhere in the state? I will be getting more information Thursday. When I was told it was back I made my oncologist give me an "expiration date", I have a lot of things I need to get in order. To be honest once she said 2 years everything after that was 'blah blah blah', etc. Your mind goes in a million different directions when hit with a big dose of reality.
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