re: Is there a disadvantage to growing up in high altitude?

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most of the women that live in the ski areas I've been to look pretty rough.

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when I stayed at a hotel in Salt Lake, there was a sign warning that sun bathing at altitude is different, that you have less air to protect you from the sun.

I think one point for the OP is that you would necessarily develop big lungs.
People live at 8 and 10 thousand in some countries.

I did a lot of yoga/pranayama as a boy and young man. when I went to get an X-ray of my lungs, I barely could fit my lungs in the rectangle you stand in front of.
Woman said I had the biggest llungs she ever X rayed.

I think you would get more of that if you lived at 8 or 10 thousand.

I lived at sea level, but did breathing exercises OBSESSIVELY from age 10 on.