re: started playing Skyrim again.

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I think NPC dialogue should change once you beat the main quest to showing at least a little respect. And if Nazeem asks me one more time about the cloud district I will cut his head off.

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There's a mod on PC that fixes the issue with the guards being jerks even after you've progressed in the game. It's called "Guard Dialog Overhaul."

Nazeem exists merely for the player to find covert ways to murder him.