re: 22LR for Self Defense?

You either have been lucky or just haven't shot enough 22 rounds. I've shot tons and tons of 22 bullets. I remember my friends uncle that works for the wildlife and fisheries would bring us bricks of 22 bullets and tell us to have fun when we were kids. I've had PLENTY fail to fire. Sometimes I'd have 5-6 out of a box that didn't shoot. Sometimes more, sometimes less, sometimes none. 22 bullets are very unreliable. That's why I wouldn't trust one with my life. My m&p 9 pro shoots every time it's supposed to.