Lack of/hard bowel movements

Going through chemo right now. I am eating regular for the most part. This has to be a side effect because I used to be like clockwork in the morning. Have had to use an enema the last 2 times I had to go and even then the results were minimal. Tried stool softeners, suppositories and today the prep concoction with the Gatorade and Miralax for a colonoscopy with zero luck. I assume at some point this could be dangerous. Don’t know what to do.