re: Boosters are over.

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It’s over, people.

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“Until such vaccines are available, and as the SARS-CoV-2 virus evolves, the composition of current COVID-19 vaccines may need to be updated, to ensure that COVID-19 vaccines continue to provide WHO-recommended levels of protection against infection and disease by VOCs, including Omicron and future variants,” the WHO said.


The panel has said that new COVID-19 vaccines need to be based on strains that are genetically and antigenically close to the circulating SARS-CoV-2 variant(s) and elicit immune responses that are broad, strong, and long-lasting in order to reduce the need for successive booster doses.

The panel has recommended vaccine manufacturers to consider a monovalent vaccine that elicits an immune response against the predominant circulating variant(s), although this option faces the challenge of the rapid emergence of SARS-CoV-2 variants and the time needed to develop a modified or new vaccine. The panel has also recommended a multivalent vaccine containing antigens from different SARS-CoV-2 VOCs; or a pan SARS-CoV-2 vaccine – a more sustainable long-term option that would effectively be variant-proof.

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