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re: Big 4-year Wegovy study out...

Posted on 5/15/24 at 12:46 pm to
Posted by WDE24
Member since Oct 2010
54183 posts
Posted on 5/15/24 at 12:46 pm to
quote:

Sitting here mid 280’s,
You sound like a pretty good candidate.

quote:

optimal weight for me is 220-230
It is probably lower than that, but that’s a great initial target, imo.
Posted by Big Scrub TX
Member since Dec 2013
33616 posts
Posted on 5/15/24 at 12:48 pm to
quote:

Office job by day, don’t stop moving til I crash at night between coaching kids sports, chores, and yard work. I try to eat better, little success or when I do I see no change. Same with working out. Love the rowing machine, can go at lunch but don’t see any changes. Mid 40’s. I know, lots of excuses. Company health screen, high bp, Dr put me on olemsartan this week. Everything else in my blood work was “normal” or within range. Sitting here mid 280’s, optimal weight for me is 220-230 10-12 years ago when I was running half marathons and had zero kids but a weak pull-out game and life going 240mph gets in the way of that type of training. shite, I’d be happy with 240’s at this point. Just need to drop 30-50 lbs that have creped up over the years that I can’t shake.
IMO, it would possibly be worth it for you. As you approach 50, I think we can agree there's going to be a decline from here on out, no matter how great you eat or exercise. So, given that, I don't view the potential downsides to be as relevant.

If going on one of these can get you down 60lbs (or more) and reduce inflammation, that seems way worth it - likely massively outweighing (no pun) some unknown downside we might be unaware of presently. There's a non-zero chance that you will just drop dead in an untimely fashion in your present condition.

Not trying to be a jerk or be scary, but I've really shifted my thinking on this. I think it is worth your serious consideration. Maybe wait 18 more months to get some more data from these studies?
Posted by lsu777
Lake Charles
Member since Jan 2004
31478 posts
Posted on 5/15/24 at 12:49 pm to
quote:

Mid 40’s. I know, lots of excuses. Company health screen, high bp, Dr put me on olemsartan this week. Everything else in my blood work was “normal” or within range. Sitting here mid 280’s, optimal weight for me is 220-230 10-12 years ago when I was running half marathons and had zero kids but a weak pull-out game and life going 240mph gets in the way of that type of training. shite, I’d be happy with 240’s at this point. Just need to drop 30-50 lbs that have creped up over the years that I can’t shake.


first how tall are out, because i doubt 220 is a good weight, prolly 200 at most and that is if you are 6'3 or taller

quote:

Trying to figure out if “the shot” is right for me…


sounds like it but you are still going to have to start making lifestyle changes if you want the habits to stick and do not want to be dependent on it rest of your life

quote:

Office job by day, don’t stop moving til I crash at night between coaching kids sports, chores, and yard work. I try to eat better, little success or when I do I see no change. Same with working out. Love the rowing machine, can go at lunch but don’t see any changes. Mid 40’s. I know, lots of excuses.


that includes dropping the excuses and starting some form of resistance training and at a minimum tracking steps

resistance training along with lots of protein is going to ensure you dont lose muscle. so its very important unless you just want to be a smaller version of your current self. also, outside of aesthetics, lifting is the best thing you can do to improve quality of life and health.

of you can lift at least 2 days a week, 2 days a week of rowing for zone 2 and hit 8k steps 5 of the 7 days...you are going to be in a great spot moving forward if you do get on the medicine

i will say, if you get on the medicine, you need to keep protein at 150g or more for you. more the better.




what are your concerns? you are atleast 75lbs overweight and prolly if being realistic, closer to 85-90. so yea the shot is right for you, short of you being willing to make a complete 180 in lifestyle in terms of diet and exercise and that doesnt sound reasonable based on your post.

if you take the shot and can go completely carnivore with veggies and small amounts of fruit, you will change your body quick
Posted by lsu777
Lake Charles
Member since Jan 2004
31478 posts
Posted on 5/15/24 at 12:54 pm to
quote:

Not trying to be a jerk or be scary, but I've really shifted my thinking on this. I think it is worth your serious consideration. Maybe wait 18 more months to get some more data from these studies?


well these medicines are new for weightloss, been around for t2d since 2005 and studied since like 79 or so. so not really anything new that will pop up
Posted by Big Scrub TX
Member since Dec 2013
33616 posts
Posted on 5/15/24 at 1:31 pm to
quote:


well these medicines are new for weightloss, been around for t2d since 2005 and studied since like 79 or so. so not really anything new that will pop up
It's not clear to me that we have true longitudinal studies of people using these in high doses for many years.

The big change is going to be when they figure out the pills. Going from daily to weekly shots is what finally caused the big recent explosion. But when the pills come, it's going to basically be everyone.
Posted by lsu777
Lake Charles
Member since Jan 2004
31478 posts
Posted on 5/15/24 at 1:32 pm to
they are out, dont think for weightloss though. will be out within next 16 months though for sure.


and yea he have data on people taking the medicine for almost 20 years straight now.
Posted by Randall Savauge
Member since Aug 2021
68 posts
Posted on 5/15/24 at 1:36 pm to
quote:

so yea the shot is right for you, short of you being willing to make a complete 180 in lifestyle in terms of diet and exercise and that doesnt sound reasonable based on your post.


Sometimes you get kicked in the teeth. I’ve never been to the doctor for a “checkup” since I was a kid before last week and now I’m on medicine to hopefully let me live to see my kids grow up. It’s say it’s time for me to make a change. Which is why I’m asking.
Posted by lsu777
Lake Charles
Member since Jan 2004
31478 posts
Posted on 5/15/24 at 1:47 pm to
quote:

Sometimes you get kicked in the teeth. I’ve never been to the doctor for a “checkup” since I was a kid before last week and now I’m on medicine to hopefully let me live to see my kids grow up. It’s say it’s time for me to make a change. Which is why I’m asking.


damn man, never went to go get levels checked or anything and you are in your 40's? thats crazy to me


yea man the medicine is 100% right for you. you can make a change and be the inspiration for your kids to live a healthy life style and be there to see your grandkids and attend their events. just have to make the choice

this isnt the OT, everyone here will do whatever they can to help
Posted by Randall Savauge
Member since Aug 2021
68 posts
Posted on 5/15/24 at 3:55 pm to
quote:

It is probably lower than that, but that’s a great initial target, imo.


Probably. I'm 5-11 but a big wide shoulder baw even when i'm not pushing 3 bills... All my extra weight us up top. 220 was my lightest since high school and that's when i was running over 40 miles per week training. It would be a comfortable goal. Less than that and i'd start to look sickly.
Posted by lsu777
Lake Charles
Member since Jan 2004
31478 posts
Posted on 5/15/24 at 4:31 pm to
Na, just think that. At 5’11 at 220 that is still 40 lbs overweight

But set an initial goal of 250, then 225. Be realistic but firm in the goals.

Yes you need to get on the medicine, quickly. You are realistically 100lbs over weight
Posted by Randall Savauge
Member since Aug 2021
68 posts
Posted on 5/15/24 at 4:42 pm to
quote:


Na, just think that. At 5’11 at 220 that is still 40 lbs overweight

But set an initial goal of 250, then 225. Be realistic but firm in the goals.

Yes you need to get on the medicine, quickly. You are realistically 100lbs over weight


settle down, these optimal body weight charts don't take body type into account. i'm not going anywhere near 200. That would be ridiculous and i would look sickly.
Posted by bamaguy17
Member since Jul 2022
751 posts
Posted on 5/15/24 at 4:48 pm to
You’d be surprised how much fat you’re carrying. 5’11 180lbs isn’t small. As a fellow caveman looking dude, I could easily lose 50 more pounds and not look sickly
Posted by WDE24
Member since Oct 2010
54183 posts
Posted on 5/15/24 at 4:51 pm to
quote:

settle down, these optimal body weight charts don't take body type into account. i'm not going anywhere near 200. That would be ridiculous and i would look sickly.
This debate is for another time. Use the medication together with lifting weights 3-4 times per week, continue your rowing 2-3 times per week, and get 7-8k steps in per day for now to move toward your goal of 220 (eta: and get 150-200 grams of protein each day). Once you get there, you will be in a better place to determine whether that’s ideal or not. I’m 6’4” and just under 220 and I lift 4x per week. I still am trying to get 10-15 leaner, but you could be different. For the time being, that debate is unimportant because you are at 280+.

Once you lose 50lbs and feel better than you have since you were in high school, then debates about how far you want to go to improve your health, physique and quality of life can be had.
This post was edited on 5/15/24 at 5:01 pm
Posted by ronricks
Member since Mar 2021
7103 posts
Posted on 5/15/24 at 4:53 pm to
I think for these guys knowing waist size is important. It’s the biggest indicator and is strongly associated with all-cause and cardiovascular mortality with or without adjustment for BMI.
Posted by lsu777
Lake Charles
Member since Jan 2004
31478 posts
Posted on 5/15/24 at 4:55 pm to
Agreed

The argument over what weight he should be at…really comes down to that. At 5’11” he should be shooting for below 35” at the naval at a minimum.
Posted by Randall Savauge
Member since Aug 2021
68 posts
Posted on 5/15/24 at 5:10 pm to
quote:

This debate is for another time.


Touche. I’d be ecstatic if we had to actually have that argument next year. That’s like arguing which national championship is the best. They all great.
Posted by WDE24
Member since Oct 2010
54183 posts
Posted on 5/15/24 at 5:34 pm to
quote:

I’d be ecstatic if we had to actually have that argument next year.
If you get dialed in on diet and exercise with the glp1, we can have the debate in about 6 months
Posted by Randall Savauge
Member since Aug 2021
68 posts
Posted on 5/15/24 at 9:01 pm to
Just checked the prices on my insurance plan, looks like we’ll be doing this the old fashioned way…
Posted by taeemwar
Dallas
Member since Apr 2010
545 posts
Posted on 5/16/24 at 6:34 am to
It sucks that a lot of insurance doesn’t pay for these drugs. I took tizrapeptide and lost 30 pounds and got back to my college weight. I am 60 years old and always worked out over the years. I feel a ton better. The money I spent was worth it.
Posted by WDE24
Member since Oct 2010
54183 posts
Posted on 5/16/24 at 7:15 am to
The good news is, it is the same plan without the medicine. Keep calories between 1800-2000 per day with 175 grams of protein, walk, lift, and be consistent.

Also, there are alternatives that make the medicine cheaper-compounding pharmacies or gray market.
This post was edited on 5/16/24 at 7:17 am
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