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Message
GLP-1 Drugs Can Be Used First for Weight Loss Says American College of Cardiology
Posted on 6/24/25 at 11:20 am
Posted on 6/24/25 at 11:20 am
quote:
— Diet and exercise no longer the main first-line strategies for weight management
quote:
The American College of Cardiology (ACC) gave popular obesity medications equal standing with diet and exercise as a first-line strategy for weight management.
In new concise clinical guidance, the ACC promoted current-generation nutrient-stimulated hormone (NuSH) therapies -- namely the GLP-1 receptor agonists semaglutide (Ozempic, Wegovy) and tirzepatide (Zepbound, Mounjaro) -- as upfront pharmacological weight management for the optimization of cardiovascular health.
"Patients should not be required to 'try and fail' lifestyle changes prior to initiating pharmacotherapy; nonetheless, lifestyle interventions should always be offered in conjunction with NuSH therapies," wrote Olivia Gilbert, MD, MSc, of Atrium Health Wake Forest Baptist Medical Center in Winston-Salem, North Carolina, and colleagues.
quote:
"More effective than lifestyle interventions and with less risk than procedure-based interventions, modern obesity medications are increasingly relevant to cardiologists for CVD modification. The intent of the current document is to provide the foundation for cardiologists to medically manage obesity using agents with proven CVD benefit," they added.
Indeed, GLP-1 drugs have been shown not only to help people shed weight and manage glucose, but also to help reduce one's cardiovascular risk. Last year, semaglutide was FDA approved for cardiovascular protectionopens in a new tab or window, alongside lifestyle intervention in people with cardiovascular disease and either obesity or overweight, based on the large SELECT trialopens in a new tab or window.
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Posted on 6/24/25 at 11:23 am to RLDSC FAN
10 pages
Posted on 6/24/25 at 11:25 am to CAD703X
Posted on 6/24/25 at 11:25 am to RLDSC FAN
Thereby shredding the last hint of credibility that they once possessed...
Posted on 6/24/25 at 11:27 am to RLDSC FAN
I honestly don’t care so long as they get the weight off and keep it off. Make them prove some physical activity to stay on it. Like check in 3x per week on an Apple Watch, FitBit, etc. if you must.
Fat people are a drag on society, increase our insurance premiums, strain our healthcare resources, and drain our tax dollars.
Fat people are a drag on society, increase our insurance premiums, strain our healthcare resources, and drain our tax dollars.
This post was edited on 6/24/25 at 11:52 am
Posted on 6/24/25 at 11:28 am to RLDSC FAN
Doesn't affect the OT. Everyone here is buff and runs marathons in under 3 hours.
Posted on 6/24/25 at 11:28 am to RLDSC FAN
You can take all the GLP-1 drugs you want but if you don't change your lifestyle you will remain fat.
Posted on 6/24/25 at 11:29 am to RLDSC FAN
a true fatty can eat through the ozempic no problem
Posted on 6/24/25 at 11:30 am to RLDSC FAN
Low T dudes on TRT about to go off...
Posted on 6/24/25 at 11:31 am to RLDSC FAN
I don’t know shite from shinola, but if it helps long term to shed a lot of weight and make it more feasible to then pursue a reasonable fitness and diet regimen then whatever works.
Posted on 6/24/25 at 11:31 am to RLDSC FAN
I had a cardiologist appointment last week, and I can confirm they are recommending it.
Posted on 6/24/25 at 11:31 am to Bestbank Tiger
quote:
Doesn't affect the OT. Everyone here is buff and runs marathons in under 3 hours
We also bang nothing lower than a 9…..
Posted on 6/24/25 at 11:31 am to DownSouthJukin
quote:
I honestly don’t care so long as they get the weight off and keep it off
But everyone will be angry they took the "easy" way out! It's more important to shame them! -The OT
Posted on 6/24/25 at 11:32 am to RLDSC FAN
It’ll never take away the high, pride and feelings of accomplishment that working out will give. Achieving your goal through your own blood, sweat, tears and grit and feeling like you earned it will always top taking a short cut.
That isn’t to say the drug can’t be effective for some people that need to make significant leaps, but working out will always be superior IMO
That isn’t to say the drug can’t be effective for some people that need to make significant leaps, but working out will always be superior IMO
Posted on 6/24/25 at 11:32 am to The Torch
quote:
You can take all the GLP-1 drugs you want but if you don't change your lifestyle you will remain fat.
This. I agree. It has to be used in conjunction with diet changes and lifestyle changes.
Posted on 6/24/25 at 11:33 am to RLDSC FAN
Many morbidly obese people , after a 100 lb weight loss caused by a GLP-1, will discover diet and exercise. Just starting backwards but ending up very often in the same place.
Posted on 6/24/25 at 11:36 am to RLDSC FAN
People goin blind on that crap. They're not mentioning that
Posted on 6/24/25 at 11:36 am to The Torch
quote:
You can take all the GLP-1 drugs you want but if you don't change your lifestyle you will remain fat.
Eating properly/reduction in calories is by far the biggest variable in the calculus. You can work out all you want and easily out-eat the workout.
Now if we're talking about total health, exercise/activity takes a larger role, but you only said "fat"
Posted on 6/24/25 at 11:39 am to Lsupimp
quote:
Many morbidly obese people , after a 100 lb weight loss caused by a GLP-1, will discover diet and exercise.
There’s no way you actually believe this
Posted on 6/24/25 at 11:39 am to RLDSC FAN
I think this is good... we aren't talking people needing to drop 10-15lbs. It should absolutely be offered (if no contraindications) for people who are 30+ on the BMI.
I don't understand the hatred of fatties plus the resistance of them having access to any effective tool available to drop weight.
No, I'm not on the shot.
My mother is tottering on the upper end of overweight/ low end obese and begged her doctor to help her out by prescribing the shot. She's already very active with her job and has attempted dieting, but at her age the weight just wouldn't budge... he refused time and again so now she's doing the telemedicine route to access it.
She'd be more comfortable taking it under the watchful eye of her physician. Maybe this recommendation will make it to where he has no excuse not to manage her on it.
I don't understand the hatred of fatties plus the resistance of them having access to any effective tool available to drop weight.
No, I'm not on the shot.
My mother is tottering on the upper end of overweight/ low end obese and begged her doctor to help her out by prescribing the shot. She's already very active with her job and has attempted dieting, but at her age the weight just wouldn't budge... he refused time and again so now she's doing the telemedicine route to access it.
She'd be more comfortable taking it under the watchful eye of her physician. Maybe this recommendation will make it to where he has no excuse not to manage her on it.
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