Munich/Interlaken or Lucerne /Italy

In the grand scheme of things, that isn't that much geography to cover (although going to Rome may be a bit of a stretch when could fly out of Milan, for instance), its is a lot of movement.

Dont think you need a travel agent. You are posting on this board, so you have google flights, AirBnB, and other resources to do booking.

Munich end of September/beginning of October would be a big party and probably loads of fun. Lucerne and Itnerlaken you may be hitting on shoulder season so it might not quite be ready for winter activities and finished with summer activities. But could score some good deals, Id imagine, as in general that is a good time to travel to Europe.

What about Munich and then into Austria...Maybe a few days in Vienna, Salzburg, etc... Fly out of vienna back home?

Regional train service is pretty good in Germany/Austria/Switzerland. It goes downhill a bit as you head south into Italy (fewer trains, older rolling stock).

Best English-language resource around for European train travel is the website The Man in Seat 61. His site has everything from time tables to route suggestions to station reviews, ticket buying tips, and so much more. Check it out: LINK

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I was thinking like 2 days in Munich, 3 days in Switzerland and around 4 days in Italy?

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That is not a schedule I would enjoy. But I'm a slow traveler. I like to settle into a place and pretend to be a local for a few days. I enjoy walking through cities, long lunches (or dinners), poking around in odd shops, visiting obscure churches with interesting art & architecture. For ex, I did an 8 day trip to Germany/Austria a couple years ago; 3 nights in Salzburg and 5 in Munich. This allowed me to use those cities as a base and take side trips.

You may feel very differently, but I'd encourage you to consider a more geographically focused itinerary (like BO suggested above, focusing on Munich/Austria/Switzerland) and spend more time in each place.

Consider that 2 days in Munich won't amount to much: your arrival day includes jet lag, which means an early-ish bedtime even if you arrive there in AM local time. You'll have a full second day, hopefully decent sleep on night two, and day 3 will mostly involve travel to the next place. Pack, check out by 10 or 11 am at the latest. No nice lunch that day, as you're schlepping luggage, then you'll take the train to Next City. Hopefully, your ABB allows for an early-ish check in, or you'll need to find a luggage drop & do some sightseeing while you wait to get into lodgings. Are you spending one night in three different places in Switzerland, or 3 days in Interlaken?

Four full days in Rome is enough to get a taste of the place and see major sites, assuming you mean a fourth night and departing on the 5th day.

Thanks for all the infomation man. I am going to show her all what y’all wrote and going to talk to her maybe about condensing the trip to one area.

Wife and I just took trip very similar sept 19-Oct 5 but in reverse order. We began in Rome => Florence => Venice => Murren, Switzerland => Munich (oktoberfest). It was our first time in Europe, and I booked everything myself. Travel agents can be helpful but we saved a lot of money and were able to book exactly what we wanted. Travel agents usually get deals through resorts and cant quite customize an itinerary usually if you have specific needs. We took trains to each destination. Switzerland required cable car up to the town of Murren. I read many threads on Rick Steves and elsewhere on exactly how and when to schedule each train. I highly recommend using the trains. I used Airbnb and booking.com to book stays. We flew through Istanbul with Turkish Airlines. No complaints there. I feel like we stayed just the right amount of time in each location and had the right combination of busy sight seeing days and relaxing days. Keep in mind Switzerland is the most expensive place you will go so plan accordingly. I can give further recommendations on scheduling and each location further if needed!

Good deal what you think should I be expecting flight wise whats a good round trip if I can get something at a good price when I see it jump on it and book it?