quote:
What do you mean processed the same? Fructose is made into F1P by fructokinase, and then is made into 2 molecules of glyceraldehyde-3-P, which can enter glycolysis. Because there is no rate-limiting step, there is an excess of triose metabolites, and fructose potentiates pyruvate kinase, leading to G3P also being being metabolized into pyruvate directly, which can go into multiple pathways. Ethanol is oxidized to acetaldehyde by alcohol dehydrogenase and then that is made into acetate by acetaldehyde dehydrogenase.

Pyruvate can become acetyl-CoA, which can lead to FA synthesis.

If you understand this then you understand that whole post you quoted is a load of bullshite. It's sugar either way, it all gets digested and if you eat too many calories it will get stored as fat.

It's a combination of things.

1) We live in an obesogenic environment. Food is everywhere, calories are cheap, and prepackaged food is literally designed by flavor scientists to get you to eat too much.

2) Technology gives most of us physically easy lives. We sit all day at desks, go home and sit on the couch, eat our calorie dense dinner, go to bed.

3) Portion distortion. Portion sizes are out of control. Restaurants, prepacked foods, etc.

4) Liquid calories, particularly in the south. We love our sweet drinks and our alcohol.

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Posted by crazy4lsu

Member since May 2005

37024 posts

Posted on 9/1/21 at 9:37 pm to Hulkklogan

quote:
If you understand this then you understand that whole post you quoted is a load of bullshite. It's sugar either way, it all gets digested and if you eat too many calories it will get stored as fat.

What? I was confused because he said they were processed the same, which I took to mean they shared metabolites. I mean, given the amount of pathways in which pyruvate is an intermediate, then nearly every exogenous metabolite could possibly be regarded as being ‘processed’ the same.

There is a meaningful difference in the nutritional content of food, and thus processing will be different. Because processing will be different, nutrition shouldn’t be regarded as purely thermodynamic, because regardless, because the body wants both homeostasis as well as conservation of energy. That people can admit that there is an excess of food designed and sold without regard for nutritional content, that should convince people regulation is needed. Instead, people will continually insist that nutrition is always a matter of individual choice, which is an insane way of thinking about it. There are meaningful biochemical processes at play. It’s not different all that different from addiction, in which there are physiologic changes, except the purview is hormonal and biochemical rather than neurological.

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