Why do they use the term "fixtures" instead of "matches," which I've seen elsewhere for soccer? Irrelevant, I know, but I'm just curious.
Just British terminology. They don't use the word "schedule" like we do.
Fixture List = Schedule
Matches = Fixture = Games
How does the prestige of the titles breakdown? Is it Champions League, EPL, Europa, FA, in that order?
I'd have it at...
Capital One Cup
...for English teams. You'll get a debate over FA vs. Europa in terms of prestige.
How likely is it that one of the, say, fifth level teams ever work its way up to the EPL?
Very unlikely. Teams have fallen from the top all the way down to that level (Luton Town comes to mind), and it's usually because of some financial issues.
That being said, a few League One and Two sides have made it to the Premier League. Southampton hit back-to-back promotions to get up there this season.
It's just really hard to make the jump from non-League (fifth level and below) back to the top, especially with today's big money game.
Does the EPL have the largest collection of both top quality talent and top quality teams in Europe?
It's a raging debate. The Premier League has been down this year (United is running away with the title, not a very good showing in the Champions League from Chelsea/City, and the remaining two teams might be on their way out next week).
The Premier League has more top clubs than other leagues, but it can be argued that the strength of the fewer top clubs in other leagues makes them equal.
For example: Man United, Man City, Chelsea, Arsenal, Tottenham and Liverpool are historically/currently huge clubs. (Tottenham is kind of a wild card, I guess.)
Compare the Big Six to say, Barcelona and Real Madrid in La Liga. (Atletico closing in and Malaga was before the financial hit.) Barcelona and Real Madrid are two of the top three clubs all-time. Which is the more powerful league? Tough to say, and it's all cyclical.
The Premier League pulls the best talent from all over the world, but the top teams in La Liga, Bundesliga, and Serie A do the same.
League comparisons turn into nasty things on this board, so I'll leave it at that.