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Started By
Message
Human Genetic Modification.....Good or Bad?
Posted on 4/22/14 at 9:25 am
Posted on 4/22/14 at 9:25 am
LINK
quote:
A genetic disease has been cured in living, adult animals for the first time using a revolutionary genome-editing technique that can make the smallest changes to the vast database of the DNA molecule with pinpoint accuracy.
Scientists have used the genome-editing technology to cure adult laboratory mice of an inherited liver disease by correcting a single “letter” of the genetic alphabet which had been mutated in a vital gene involved in liver metabolism.
quote:
Since then there has been an explosion of interest in the technology because it is such a simple method of changing the individual letters of the human genome – the 3 billion “base pairs” of the DNA molecule – with an accuracy equivalent to correcting a single misspelt word in a 23-volume encyclopaedia.
quote:
“I think there will be a lot of progress made in the coming one to two years in using this approach for therapeutics and other real-world applications,” she added.
Delivering Crispr safely and efficiently to affected human cells is seen as one of the biggest obstacles to its widespread use in medicine.
4
Posted on 4/22/14 at 9:30 am to beejon
quote:
with an accuracy equivalent to correcting a single misspelt word in a 23-volume encyclopaedia.
Single?
Sorry, couldn't resist
ETA - Non U.S. links blocked
but I'll take my lumps. Had no idea we had so many Brits congregating here.This post was edited on 4/22/14 at 10:00 am
Posted on 4/22/14 at 9:36 am to Judge Smails
quote:
Single?
Sorry, couldn't resist
LOL! Maybe that was a random mutation of the ink?
ETA: I think that was the British weird spelling of the words. The article was from The Independent.
This post was edited on 4/22/14 at 9:40 am
Posted on 4/22/14 at 9:40 am to Judge Smails
That's the original spelling of encyclopedia, btw. Americans dumbed it down by removing the 'a'. Not sure on "misspelt".
Posted on 4/22/14 at 9:41 am to gorillacoco
quote:
Not sure on "misspelt".
Looks to be the same. So LOL at 1st response
ETA - British sometimes spell things differently, and the link is .uk
This post was edited on 4/22/14 at 9:43 am
Posted on 4/22/14 at 9:44 am to Judge Smails
Nice job, moran.
Posted on 4/22/14 at 9:46 am to beejon
Research Plum Island
LINK
LINK
quote:
Plum Island Animal Disease Center of New York (PIADCNY) is a United States federal research facility dedicated to the study of animal diseases. It is part of the DHS Directorate for Science and Technology.
Since 1954, the center has had the goal of protecting America's livestock from animal diseases. During the Cold War a secret biological weapons program targeting livestock was conducted at the site. This program has been the subject of controversy.
Posted on 4/22/14 at 9:48 am to Tigerlaff
I'm for it.
Posted on 4/22/14 at 9:51 am to white perch
It's a very good thing. Could lead the elimination of a lot of diseases and such.
Posted on 4/22/14 at 9:53 am to Judge Smails
quote:
Single?
Sorry, couldn't resist
Posted on 4/22/14 at 10:28 am to GEAUXmedic
Its huge news for lots of reasons. My son was born with Cystic Fibrosis, a genetic disease, and so far there is no cure. There have been lots of progress made through research and clinical trials but more has to be done. Something like this could fix the genetic mutation and make his CF go away. Carry on scientist! Carry on!
This post was edited on 4/22/14 at 10:29 am
Posted on 6/6/14 at 11:18 am to beejon
I was coming to post about CRISPR (Clustered, Regularly Interspaced Short Palindromic Repeats), and was surprised to already find a thread about it; however, I was not surprised to find that it was only a few posts long
Specifically, I was going to point out that there are always these huge threads when something that is 10 years old gets published in Time or some periodical with Time in the title and is touted as the next big thing. People start arguing that it is definitely going to cure cancer blah blah blah because they read an article and it said so, even though the author of that article didn't read nor could he understand the science even if he did read the original research.
Well you ignorant sons of bitches, CRISPR technology really is the next big thing, and it is going to test ethical boundaries for everyone, even those who invented it. CRISPR allows for extremely specific modifications to a genome which can then be implanted into an empty host cell which can then be implanted into a surrogate and Boom!! clone with the modified genome. CRISPR has the potential to safely cure gene-based diseases before you are born. Are you predisposed for cancer? Sickle Cell? SCID? Would you want these genes fixed in your unborn children? How much would you pay? Want a blue-eyed baby? This is the first technology that truthfully has the potential to allow for custom children.... Are you a weakling? Want your child to be stronger? we have a gene correction for that... Aside from curing/preventing diseases, CRISPR will aid in the development of GM crops, foods, etc. that will be much safer and possibly enable the ability to harvest crops in previously unsuitable areas.
This technology has already proven to be safe and successful and is on the verge of becoming a transformative discovery. Anywho, I am sure you people will still not pick up on it, but CRISPR is about to change the world. Sure wish I invented it.
Specifically, I was going to point out that there are always these huge threads when something that is 10 years old gets published in Time or some periodical with Time in the title and is touted as the next big thing. People start arguing that it is definitely going to cure cancer blah blah blah because they read an article and it said so, even though the author of that article didn't read nor could he understand the science even if he did read the original research.
Well you ignorant sons of bitches, CRISPR technology really is the next big thing, and it is going to test ethical boundaries for everyone, even those who invented it. CRISPR allows for extremely specific modifications to a genome which can then be implanted into an empty host cell which can then be implanted into a surrogate and Boom!! clone with the modified genome. CRISPR has the potential to safely cure gene-based diseases before you are born. Are you predisposed for cancer? Sickle Cell? SCID? Would you want these genes fixed in your unborn children? How much would you pay? Want a blue-eyed baby? This is the first technology that truthfully has the potential to allow for custom children.... Are you a weakling? Want your child to be stronger? we have a gene correction for that... Aside from curing/preventing diseases, CRISPR will aid in the development of GM crops, foods, etc. that will be much safer and possibly enable the ability to harvest crops in previously unsuitable areas.
This technology has already proven to be safe and successful and is on the verge of becoming a transformative discovery. Anywho, I am sure you people will still not pick up on it, but CRISPR is about to change the world. Sure wish I invented it.
Posted on 6/6/14 at 11:44 am to Judge Smails
quote:
ETA - Non U.S. links blocked but I'll take my lumps. Had no idea we had so many Brits congregating here.
No need for lumps, you were correct IMO
Posted on 6/6/14 at 11:47 am to beejon
Really, the only answer to this is both.
Depends on the intentions behind, implementation of, and accuracy of the changes.
Making humans invulnerable to disease? GREAT, take my funding
Slowly creating a genetically superior class of people based on who can afford these pricey genetic changes? Whoa now, Hitler.
Depends on the intentions behind, implementation of, and accuracy of the changes.
Making humans invulnerable to disease? GREAT, take my funding
Slowly creating a genetically superior class of people based on who can afford these pricey genetic changes? Whoa now, Hitler.
This post was edited on 6/6/14 at 11:50 am
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